Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity

A Leimbach, J Hacker, U Dobrindt - Between pathogenicity and …, 2013 - Springer
Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless
commensal as well as different pathogenic variants with the ability to either cause intestinal …

Virulence and Fitness Determinants of Uropathogenic Escherichia coli

S Subashchandrabose… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTIs) are one of the most common bacterial infections affecting
humans, and uropathogenic Escherichia coli (UPEC) is the etiological agent in 75% to 95 …

Bacterial genome instability

E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …

Urinary tract infection

K Gupta, L Grigoryan, B Trautner - Annals of internal medicine, 2017 - acpjournals.org
Urinary tract infections (UTIs) are common in both inpatient and outpatient settings. This
article provides an evidence-based, clinically relevant overview of management of UTIs …

Phase and antigenic variation in bacteria

MW Van Der Woude, AJ Bäumler - Clinical microbiology reviews, 2004 - Am Soc Microbiol
Phase and antigenic variation result in a heterogenic phenotype of a clonal bacterial
population, in which individual cells either express the phase-variable protein (s) or not, or …

Treatment and prevention of urinary tract infection with orally active FimH inhibitors

CK Cusumano, JS Pinkner, Z Han, SE Greene… - Science translational …, 2011 - science.org
Chronic and recurrent urinary tract infections pose a serious medical problem because there
are few effective treatment options. Patients with chronic urinary tract infections are …

Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract

MC Lane, CJ Alteri, SN Smith… - Proceedings of the …, 2007 - National Acad Sciences
Uropathogenic Escherichia coli (UPEC) cause most uncomplicated urinary tract infections
(UTIs) in humans. Because UTIs are considered to occur in an ascending manner, flagellum …

Extraintestinal Pathogenic Escherichia coli

JL Smith, PM Fratamico, NW Gunther - Foodborne pathogens and …, 2007 - liebertpub.com
Extraintestinal pathogenic Escherichia coli (ExPEC) possesses virulence traits that allow it to
invade, colonize, and induce disease in bodily sites outside of the gastrointestinal tract …

Transcriptome of Uropathogenic Escherichia coli during Urinary Tract Infection

JA Snyder, BJ Haugen, EL Buckles… - Infection and …, 2004 - Am Soc Microbiol
ABSTRACT A uropathogenic Escherichia coli strain CFT073-specific DNA microarray that
includes each open reading frame was used to analyze the transcriptome of CFT073 …