Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …

Type 1 diabetes mellitus (T1DM) arises from the failure of pancreatic β-cells to produce
adequate insulin, usually as a consequence of extensive pancreatic β-cell destruction …

Increasing lines of evidence identified that dexmedetomidine (DEX) exerted protective
effects against sepsis-stimulated acute lung injury via anti-inflammation, anti-oxidation and …

Spermatogonial stem cells (SSCs) are the only adult stem cells that pass genes to the next
generation and can be used in assisted reproductive technology and stem cell therapy. SSC …

Abstract Treatment of cancer in young adults is associated with several side effects,
particularly in the reproductive system. Detrimental effects of chemotherapy on the germ …

Ferritinophagy is one of the most recent molecular mechanisms affecting cardiac function. In
addition, it is one of the pathways by which doxorubicin, one of the anticancer drugs …

Aim Cyclophosphamide (CP)-induced cystitis is a challenging clinical problem involving
inflammation and dysfunction of bladder. Trimetazidine (TMZ) is an anti-anginal drug with …

Combination chemotherapy seems to be a beneficial choice for some cancer patients
particularly when the drugs target different processes of oncogenesis; patients treated with …

Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence
that leads to significant morbidity and mortality. The liver plays a vital role in glycemic …

The main disadvantage of doxorubicin (DOX) is that it has cardiotoxic side effects. Our aim is
to evaluate the cardioprotective effects of adrenomedullin (ADM) and to compare these …