Antibody secreting plasma cell plays an indispensable role in humoral immunity. As
activated B cell undergoes germinal center reaction and develops into plasma cell, it …

Genomic instability, a well-established hallmark of human cancer, is also a driving force in
the natural history of multiple myeloma (MM)–a difficult to treat and in most cases fatal …

The Cereblon-CRL4 complex has been studied predominantly with regards to thalidomide
treatment of multiple myeloma. Nevertheless, the role of Cereblon-CRL4 in Thalidomide …

Multiple myeloma (MM) is a haematologic malignancy characterized by the presence of
atypical plasma cells. Basigin (BSG, CD147) controls lactate export through the …

Multiple myeloma (MM) is an aggressive cancer characterised by malignancy of the plasma
cells and a rising global incidence. The gold standard for optimum response is aggressive …

BACKGROUND Erythema nodosum leprosum (ENL) is an acute and systemic inflammatory
reaction of leprosy characterised by painful nodules and involvement of various organs …

Thalidomide is commonly used in treatment of multiple myeloma (MM). This study aimed to
analyse the influence of clinical and molecular factors‐single nucleotide polymorphisms …

Abstract Carfilzomib-lenalidomide-dexamethasone (KRd) therapy has yielded promising
results in patients with newly diagnosed multiple myeloma (NDMM). Cereblon (CRBN) is the …

Skin aging is a physiological process marked by changes in the skin's structure, giving rise
to the characteristics of skin aging, such as pigmentation. Genome-Wide Association Studies …

Cereblon is a primary molecular target for immunomodulatory drugs. The aim of this study
was to evaluate the influence of selected clinical and molecular factors including single …