Abstract 2021 marks the 30th anniversary of the original development of the Banff
Classification of Kidney Allograft Pathology, when in August 1991 a group of pathologists …

Detection of mismatched human leukocyte antigens by adaptive immune cells is considered
as the main cause of transplant rejection, leading to either T-cell mediated rejection or …

For three decades, the international Banff classification has been the gold standard for
kidney allograft rejection diagnosis, but this system has become complex over time with the …

Background Acute tubulointerstitial nephritis (AIN) is one of the few causes of acute kidney
injury with diagnosis-specific treatment options. However, due to the need to obtain a kidney …

Background Cross-species immunological incompatibilities have hampered pig-to-human
xenotransplantation, but porcine genome engineering recently enabled the first successful …

This review outlines the molecular disease states in kidney transplant biopsies as
documented in the development of the Molecular Microscope Diagnostic System (MMDx) …

The prevalence and long-term impact of T cell–mediated rejection (TCMR) is poorly defined
in the modern era of tacrolimus/mycophenolate-based maintenance therapy. This …

This review describes the development of the Molecular Microscope Diagnostic System
(MMDx) for heart transplant endomyocardial biopsies (EMBs). MMDx-Heart uses …

To the editor: We read with great interest the report of Negrea and Rovin of 2 cases of IgA
nephropathy with gross hematuria following the Moderna vaccine for severe acute …

Background To seek insights into the pathogenesis of chronic active antibody–mediated
rejection (CAMR), we performed mRNA analysis and correlated transcripts with pathologic …