Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

A review of different models derived from classical Kolmogorov, Johnson and Mehl, and Avrami (KJMA) theory to recover physical meaning in solid‐state …

JS Blázquez, FJ Romero, CF Conde… - physica status solidi …, 2022 - Wiley Online Library
The classical theory of solid‐state transformation based on nucleation and growth
processes, developed by Kolmogorov, Johnson and Mehl, and Avrami (KJMA theory), is …

A chromatin structure‐based model accurately predicts DNA replication timing in human cells

Y Gindin, MS Valenzuela, MI Aladjem… - Molecular systems …, 2014 - embopress.org
The metazoan genome is replicated in precise cell lineage‐specific temporal order.
However, the mechanism controlling this orchestrated process is poorly understood as no …

Human genome replication proceeds through four chromatin states

H Julienne, A Zoufir, B Audit… - PLoS computational …, 2013 - journals.plos.org
Advances in genomic studies have led to significant progress in understanding the
epigenetically controlled interplay between chromatin structure and nuclear functions …

On the interplay of the DNA replication program and the intra-S phase checkpoint pathway

D Ciardo, A Goldar, K Marheineke - Genes, 2019 - mdpi.com
DNA replication in eukaryotes is achieved by the activation of multiple replication origins
which needs to be precisely coordinated in space and time. This spatio-temporal replication …

Multiscale analysis of genome-wide replication timing profiles using a wavelet-based signal-processing algorithm

B Audit, A Baker, CL Chen, A Rappailles, G Guilbaud… - Nature protocols, 2013 - nature.com
In this protocol, we describe the use of the LastWave open-source signal-processing
command language (http://perso. ens-lyon. fr/benjamin. audit/LastWave/) for analyzing …

[HTML][HTML] Structural organization of human replication timing domains

RE Boulos, G Drillon, F Argoul, A Arneodo, B Audit - FEBS letters, 2015 - Elsevier
Recent analysis of genome-wide epigenetic modification data, mean replication timing
(MRT) profiles and chromosome conformation data in mammals have provided increasing …

Genome replication in asynchronously growing microbial populations

FG Pflug, D Bhat, S Pigolotti - PLOS Computational Biology, 2024 - journals.plos.org
Biological cells replicate their genomes in a well-planned manner. The DNA replication
program of an organism determines the timing at which different genomic regions are …

Stochasticity of replication forks' speeds plays a key role in the dynamics of DNA replication

R Yousefi, M Rowicka - PLoS computational biology, 2019 - journals.plos.org
Eukaryotic DNA replication is elaborately orchestrated to duplicate the genome timely and
faithfully. Replication initiates at multiple origins from which replication forks emanate and …

Cell-to-cell variability and robustness in S-phase duration from genome replication kinetics

Q Zhang, F Bassetti, M Gherardi… - Nucleic acids …, 2017 - academic.oup.com
Genome replication, a key process for a cell, relies on stochastic initiation by replication
origins, causing a variability of replication timing from cell to cell. While stochastic models of …