Affinity chromatography is among the most powerful separation techniques, achieving the
finest separation with high yields even in the most challenging feed streams. Incorporating …

Solid phase screenings of one bead one compound (OBOC) libraries have been widely
used to find ligands with pharmacological and analytical uses, and to purify or detect …

This work presents the selection and characterization of erythropoietin (EPO)-binding cyclic
peptide ligands. The sequences were selected by screening a focused library of cyclic …

This work presents the use of peptide ligand HWRGWV and its cognate sequences to
develop affinity adsorbents that compete with Protein A in terms of binding capacity and …

The rapid expansion of CRISPR in biotechnology, medicine, and bioprocessing poses an
urgent need for advanced manufacturing of Cas nucleases. The lack of Cas-targeting …

In the past decade, new approaches to the discovery and development of vaccines have
transformed the field. Advances during the COVID‐19 pandemic allowed the production of …

We report herein a novel ChemMatrix® Rink resin functionalised with two phenylboronate
(PhB) moieties linked on the N-α and N-ε amino functions of a lysine residue to specifically …

Capture of host cell proteins (HCPs) from cell culture production harvests is critical to ensure
the maximum levels specified by international regulatory bodies of product purity for …

Since introduction of sinapinic acid (SA) and α‐cyano‐4‐hydroxycinnamic acid as matrices,
successful application of matrix‐assisted laser desorption/ionization mass spectrometry …

One bead–one peptide libraries allow the screening of suitable ligands for any target
protein. Short cyclic peptides are ideal ligands for affinity chromatography because of their …