It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

The complexity of human DNA has been affected by aerobic metabolism, including
endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an …

Persistent, sub-clinical inflammation, as indicated by higher circulating levels of
inflammatory mediators, is a prominent risk factor for several chronic diseases, as well as …

Redox reactions control fundamental processes of human biology. Therefore, it is safe to
assume that the responses and adaptations to exercise are, at least in part, mediated by …

Physical exercise increases the cellular production of reactive oxygen species (ROS) in
muscle, liver, and other organs. This is unlikely due to increased mitochondrial production …

Muscle fatigue is defined as a decrease in maximal force or power generated in response to
contractile activity, and it is a risk factor for the development of musculoskeletal injuries. One …

Peripheral arterial disease (PAD) is a common vascular disease that reduces blood flow
capacity to the legs of patients. PAD leads to exercise intolerance that can progress in …

Skeletal muscles require the proper production and distribution of energy to sustain their
work. To ensure this requirement is met, mitochondria form large networks within skeletal …

As a greater proportion of the population is surviving to very old ages, the public health
burden of aging-related disability and the associated increases in utilization of medical care …

The central aim of this review is to address the highly multidisciplinary topic of redox biology
as related to exercise using an integrative and comparative approach rather than focusing …