[HTML][HTML] Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes

M Ribasés, M Mitjans, CA Hartman, MS Artigas… - Neuroscience & …, 2023 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …

Genetics of ADHD: what should the clinician know?

O Grimm, TM Kranz, A Reif - Current psychiatry reports, 2020 - Springer
Abstract Purpose of Review Attention deficit hyperactivity disorder (ADHD) shows high
heritability in formal genetic studies. In our review article, we provide an overview on …

Rare de novo damaging DNA variants are enriched in attention-deficit/hyperactivity disorder and implicate risk genes

E Olfson, LC Farhat, W Liu, LA Vitulano, G Zai… - Nature …, 2024 - nature.com
Research demonstrates the important role of genetic factors in attention-deficit/hyperactivity
disorder (ADHD). DNA sequencing of families provides a powerful approach for identifying …

The known and unknown about attention deficit hyperactivity disorder (ADHD) genetics: a special emphasis on Arab population

NN Mahrous, A Albaqami, RA Saleem, B Khoja… - Frontiers in …, 2024 - frontiersin.org
Attention deficit hyperactivity disorder (ADHD) is a clinically and genetically heterogeneous
neurodevelopmental syndrome characterized by behavioral appearances such as …

Recent developments in the genetics of attention‐deficit hyperactivity disorder

O Grimm, S Kittel‐Schneider… - Psychiatry and Clinical …, 2018 - Wiley Online Library
Attention‐deficit hyperactivity disorder (ADHD) is a developmental psychiatric disorder that
affects children and adults. ADHD is one of the psychiatric disorders with the strongest …

Whole exome sequencing in ADHD trios from single and multi-incident families implicates new candidate genes and highlights polygenic transmission

BR Al-Mubarak, A Omar, B Baz… - European Journal of …, 2020 - nature.com
Several types of genetic alterations occurring at numerous loci have been described in
attention deficit hyperactivity disorder (ADHD). However, the role of rare single nucleotide …

Structure and functions of sidekicks

M Yamagata - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Many of the immunoglobulin superfamily (IgSF) molecules play pivotal roles in cell
communication. The Sidekick (Sdk) gene, first described in Drosophila, encodes the single …

Convergence and divergence in the genetics of psychiatric disorders from pathways to developmental stages

S Shohat, A Amelan, S Shifman - Biological psychiatry, 2021 - Elsevier
In the past decade, the identification of susceptibility genes for psychiatric disorders has
become routine, but understanding the biology underlying these discoveries has proven …

EWAS of monozygotic twins implicate a role of mTOR pathway in pathogenesis of tic spectrum disorder

M Hildonen, AM Levy, CS Hansen, J Bybjerg-Grauholm… - Genes, 2021 - mdpi.com
Tic spectrum disorder (TSD) is an umbrella term which includes Gilles de la Tourette
syndrome (GTS) and chronic tic disorder (CTD). They are considered highly heritable, yet …

The Implicated Roles of Cell Adhesion Molecule 1 (CADM1) Gene and Altered Prefrontal Neuronal Activity in Attention-Deficit/Hyperactivity Disorder: A “Gene–Brain …

J Jin, L Liu, W Chen, Q Gao, H Li, Y Wang… - Frontiers in genetics, 2019 - frontiersin.org
Background: Genes related to cell adhesion pathway have been implicated in the genetic
architecture of attention-deficit/hyperactivity disorder (ADHD). Cell adhesion molecule 1 …