Lutein and zeaxanthin and their roles in age-related macular degeneration—neurodegenerative disease

M Mrowicka, J Mrowicki, E Kucharska, I Majsterek - Nutrients, 2022 - mdpi.com
Lutein and zeaxanthin belong to the xanthophyll family of carotenoids, which are pigments
produced by plants. Structurally, they are very similar, differing only slightly in the …

Terpenoids as potential geroprotectors

E Proshkina, S Plyusnin, T Babak, E Lashmanova… - Antioxidants, 2020 - mdpi.com
Terpenes and terpenoids are the largest groups of plant secondary metabolites. However,
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …

[HTML][HTML] Nutritional cognitive neuroscience of aging: Focus on carotenoids and cognitive frailty

MC Polidori, W Stahl, HR Griffiths - Redox Biology, 2021 - Elsevier
The term „nutritional cognitive neuroscience” was recently established to define a research
field focusing on the impact of nutrition on cognition and brain health across the life span. In …

[HTML][HTML] Roles of macular carotenoids in brain function throughout the lifespan: A review of recent research

L Tan, Y Zhang, R Dawson, L Kong - Journal of Agriculture and Food …, 2023 - Elsevier
Lutein, zeaxanthin, and meso-zeaxanthin are carotenoids stored in the macular pigment of
the retina, recognized for their essential role in maintaining optimal eye health. These …

Lutein has a positive impact on brain health in healthy older adults: a systematic review of randomized controlled trials and cohort studies

A Yagi, R Nouchi, L Butler, R Kawashima - Nutrients, 2021 - mdpi.com
A previous systematic review revealed that lutein intake leads to improved cognitive function
among older adults. However, the association between lutein intake and brain health …

Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study

CE Zwilling, J Wu, AK Barbey - npj Aging, 2024 - nature.com
The emerging field of Nutritional Cognitive Neuroscience aims to uncover specific foods and
nutrients that promote healthy brain aging. Central to this effort is the discovery of nutrient …

Partial mitigation of oxidized phospholipid-mediated mitochondrial dysfunction in neuronal cells by oxocarotenoids

OS Ademowo, IHK Dias… - Journal of …, 2020 - content.iospress.com
Mitochondria are important (patho) physiological sources of reactive oxygen species (ROS)
that mediate mitochondrial dysfunction and phospholipid oxidation; an increase in …

Can diet supplements of macular pigment of lutein, zeaxanthin, and meso-zeaxanthin affect cognition?

H Wang, G Wang, R Billings, D Li… - Journal of …, 2022 - content.iospress.com
Background: Lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) are collectively called
macular pigment. MZ can be converted from L in the macula. In the recent decade, many …

Plasma carotenoids and medial temporal lobe atrophy in older adults

A Thomas, C Proust-Lima, M Baillet, C Helmer… - Clinical Nutrition, 2021 - Elsevier
Background & aims Carotenoids are vegetable pigments with neuroprotective properties.
Clinical studies found efficacy of specific carotenoids on improving brain perfusion and …

A multi-method investigation of the personality correlates of functional ability in older adults

MA Gogniat, CS Hyatt, KR Jean, VJ Rodriguez… - Clinical …, 2020 - Taylor & Francis
Objectives This study evaluated the role of personality in predicting functional ability (FA) in
older adults using self-report, collateral report, and performance-based measures of FA …