What is currently known about the role of CXCL10 in SARS-CoV-2 infection?

M Gudowska-Sawczuk, B Mroczko - International Journal of Molecular …, 2022 - mdpi.com
Dysregulation of the immune response plays an important role in the progression of SARS-
CoV-2 infection. A “cytokine storm”, which is a phenomenon associated with uncontrolled …

COVID-19 biomarkers at the crossroad between patient stratification and targeted therapy: the role of validated and proposed parameters

M Rizzi, D D'Onghia, S Tonello, R Minisini… - International Journal of …, 2023 - mdpi.com
Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

Plasma biomarkers for systemic inflammation in COVID‐19 survivors

J Zhao, M Schank, L Wang, X Dang… - PROTEOMICS …, 2022 - Wiley Online Library
Background While the majority of COVID‐19 patients fully recover from the infection and
become asymptomatic, a significant proportion of COVID‐19 survivors experience a broad …

Prognostic markers in hospitalized COVID‐19 patients: the role of IP‐10 and C‐reactive protein

M Rizzi, M Costanzo, S Tonello, E Matino… - Disease …, 2022 - Wiley Online Library
Background. SARS‐CoV‐2 is responsible for COVID‐19, a clinically heterogeneous
disease, ranging from being completely asymptomatic to life‐threating manifestations. An …

Novel long non-coding RNAs associated with inflammation and macrophage activation in human

A Chini, P Guha, VS Malladi, Z Guo, SS Mandal - Scientific Reports, 2023 - nature.com
Inflammation plays a central role in immune response and macrophage activation. Emerging
studies demonstrate that along with proteins and genomic factors, noncoding RNA are …

Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19

F Hersi, A Sebastian, H Tarazi, V Srinivasulu… - European Journal of …, 2023 - Elsevier
The recent emergence of different SARS-CoV-2 variants creates an urgent need to develop
more effective therapeutic agents to prevent COVID-19 outbreaks. Among SARS-CoV-2 …

Cortical-blood vessel assembloids exhibit Alzheimer's disease phenotypes by activating glia after SARS-CoV-2 infection

D Kong, KH Park, DH Kim, NG Kim, SE Lee… - Cell Death …, 2023 - nature.com
A correlation between COVID-19 and Alzheimer's disease (AD) has been proposed recently.
Although the number of case reports on neuroinflammation in COVID-19 patients has …

Mussel-inspired adhesive drug-loaded hydrogels for oral ulcers treatment

Z Wang, X Han, W Xiao, P Wang, J Wang, D Zou… - Acta Biomaterialia, 2024 - Elsevier
Oral aphthous ulcers are common mucosal lesions that cause pain and discomfort. There
are diverse biomaterials and drug treatments for oral ulcers used in both research and …

Dietary glucose ameliorates impaired intestinal development and immune homeostasis disorders induced by chronic cold stress in pig model

G Sun, X Song, Y Zou, T Teng, L Jiang… - International Journal of …, 2022 - mdpi.com
Endotherms are easily challenged by chronic cold stress. In this study, the development and
injury of the small intestine in the Min pig model and Yorkshire pig model under chronic cold …

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

J Tian, BJ Dillion, J Henley, L Comai… - Frontiers in …, 2022 - frontiersin.org
Gamma-aminobutyric acid (GABA) and GABA-receptors (GABA-Rs) form a major
neurotransmitter system in the brain. GABA-Rs are also expressed by 1) cells of the innate …