The merging of photoredox and nickel catalysis has revolutionized the field of C–C cross‐
coupling. However, in comparison to the development of synthetic methods, detailed …

Conspectus Homogeneous metal-mediated organometallic reactions represent a very large
and diverse reaction class. Density functional theory calculations are now routinely carried …

Difluorocarbene has important applications in pharmaceuticals, agrochemicals and
materials, but all these applications proceed using just a few types of reaction by taking …

Herein, we report a Cu‐mediated trifluoromethylation of carbonyl‐type compounds and
unactivated olefins enabled by visible‐light irradiation via σ C (sp3)− C bond …

Computational chemistry has emerged as a powerful tool to gain insight on the molecular
details of complex catalytic mechanisms—to uncover novel catalysis concepts or assist in …

The observation of post-transition-state dynamic effects in the context of metal-based
transformation is rare. To date, there has been no reported case of a dynamic effect for the …

The development of innovative fluorination strategies is greatly dependent also on the
availability, safety and practicability of available fluorinating reagents. We herein show a …

Silver salts are one of the most widely used additives in Pd-catalysed transformations. Apart
from acting as a halide scavenger and/or an external oxidant, over the past decade it has …

Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Bromides with TMSCF2H | The
Journal of Organic Chemistry ACS ACS Publications C&EN CAS Find my institution Log In The …

While the transmetalation of Ni (II) intermediates constitutes a key elementary step, there are
limited data and insights available on the precise underlying mechanism of transmetalation …