Development, circuitry, and function of the zebrafish cerebellum

S Pose-Méndez, P Schramm, K Valishetti… - Cellular and Molecular …, 2023 - Springer
The cerebellum represents a brain compartment that first appeared in gnathostomes (jawed
vertebrates). Besides the addition of cell numbers, its development, cytoarchitecture …

Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain

F Svara, D Förster, F Kubo, M Januszewski… - Nature …, 2022 - nature.com
Dense reconstruction of synaptic connectivity requires high-resolution electron microscopy
images of entire brains and tools to efficiently trace neuronal wires across the volume. To …

The Visual Systems of Zebrafish

H Baier, EK Scott - Annual Review of Neuroscience, 2024 - annualreviews.org
The zebrafish visual system has become a paradigmatic preparation for behavioral and
systems neuroscience. Around 40 types of retinal ganglion cells (RGCs) serve as matched …

Retina-derived signals control pace of neurogenesis in visual brain areas but not circuit assembly

S Sherman, I Arnold-Ammer, MW Schneider… - Nature …, 2023 - nature.com
Brain development is orchestrated by both innate and experience-dependent mechanisms,
but their relative contributions are difficult to disentangle. Here we asked if and how central …

Mitochondrial proteins encoded by the 22q11. 2 neurodevelopmental locus regulate neural stem and progenitor cell proliferation

PD Campbell, I Lee, S Thyme, M Granato - Molecular psychiatry, 2023 - nature.com
Microdeletion of a 3Mb region encompassing 45 protein-coding genes at chromosome
22q11. 2 (22q11. 2DS) predisposes individuals to multiple neurodevelopmental disorders …

Designing a Hybrid Chain Reaction Probe for Multiplex Transcripts Assay with High-Level Imaging

D Cao, X Qin, W Wang, Y Zhang, S Peng, H Gong… - ACS …, 2023 - ACS Publications
The hybrid chain reaction (HCR), an isothermal and enzyme-free amplification strategy, has
found extensive use in fluorescent in situ hybridization (FISH) assays. However, the existing …

The calcium-sensing receptor (CaSR) regulates zebrafish sensorimotor decision making via a genetically defined cluster of hindbrain neurons

H Shoenhard, RA Jain, M Granato - Cell reports, 2022 - cell.com
Decision making is a fundamental nervous system function that ranges widely in complexity
and speed of execution. We previously established larval zebrafish as a model for …

Visual recognition of social signals by a tectothalamic neural circuit

JM Kappel, D Förster, K Slangewal, I Shainer, F Svara… - Nature, 2022 - nature.com
Social affiliation emerges from individual-level behavioural rules that are driven by
conspecific signals,,,–. Long-distance attraction and short-distance repulsion, for example …

Recurrent network interactions explain tectal response variability and experience-dependent behavior

A Zylbertal, IH Bianco - Elife, 2023 - elifesciences.org
Response variability is an essential and universal feature of sensory processing and
behavior. It arises from fluctuations in the internal state of the brain, which modulate how …

CRISPR/Cas9-based QF2 knock-in at the tyrosine hydroxylase (th) locus reveals novel th-expressing neuron populations in the zebrafish mid- and hindbrain

C Altbürger, J Holzhauser, W Driever - Frontiers in Neuroanatomy, 2023 - frontiersin.org
Catecholaminergic neuron clusters are among the most conserved neuromodulatory
systems in vertebrates, yet some clusters show significant evolutionary dynamics. Because …