Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …

The TMEM16A/anoctamin-1 calcium-activated chloride channel (CaCC) contributes to a
range of vital functions, such as the control of vascular tone and epithelial ion transport. The …

Mutations in ANO5 (TMEM16E) cause limb-girdle muscular dystrophy R12. Defective
plasma membrane repair is a likely mechanism. Using myofibers from Ano5 knockout mice …

TMEM16A Ca2+-activated chloride channels are involved in multiple cellular functions and
are proposed targets for diseases such as hypertension, stroke, and cystic fibrosis. This …

Sensing smells of foods, prey, or predators determines animal survival. Olfactory sensory
neurons in the olfactory epithelium (OE) detect odorants, where cAMP and Ca 2+ play a …

Of the many crucial functions of the ER, homeostasis of physiological calcium increase is
critical for signaling. Plasma membrane (PM) injury causes a pathological calcium influx …

ANO5 encodes transmembrane protein 16E (TMEM16E), an intracellular calcium-activated
chloride channel in the endoplasmic reticulum. Mutations in ANO5 are associated with …

Anoctaminopathy-5 refers to a group of hereditary skeletal muscle or bone disorders due to
mutations in the anoctamin 5 (ANO5)-encoding gene, ANO5. ANO5 is a 913-amino acid …

Simple Summary Diarrhea and vomiting caused by Escherichia coli (E. coli) F17 are
considered significant threats to animal farming. In the present study, RNA-Seq was …

TMEM16 proteins, which function as Ca2+-activated Cl− channels are involved in regulating
a wide variety of cellular pathways and functions. The modulators of Cl− channels can be …