Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a promising
source of new antimicrobials in the face of rising antibiotic resistance. Here, we report a …

Cytochrome P450 enzymes (P450s) catalyze diverse oxidative cross-coupling reactions
between aromatic substrates in the natural product biosynthesis. Specifically, P450s install …

Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a
fascinating group of natural products that exhibit diverse structural features and bioactivities …

Natural products (NPs) produced by microorganisms and plants are a major source of drugs,
herbicides, and fungicides. Thanks to recent advances in DNA sequencing, bioinformatics …

Microviridins and other ω-ester-linked peptides, collectively known as graspetides, are
characterized by side-chain–side-chain linkages installed by ATP-grasp enzymes. Here we …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a large and
diverse class of natural products of ribosomal origin. In the past decade, various …

Moroidin is a bicyclic plant octapeptide with tryptophan side-chain cross-links, originally
isolated as a pain-causing agent from the Australian stinging tree Dendrocnide moroides …

Recent efforts in genome mining of ribosomally synthesized and post-translationally
modified peptides (RiPPs) have expanded the diversity of post-translational modification …