Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

Testicular germ cell tumours are at the crossroads of developmental and neoplastic
processes. Their cause has not been fully elucidated but differences in incidences suggest …

PURPOSE Previous studies suggested that serum levels of microRNA (miR)-371a-3p (so-
called M371 test) have a much higher sensitivity and specificity than the classic markers of …

Testicular germ cell tumors (TGCTs) are the most common testicular neoplasms in
adolescents and young males. Understanding the genetic basis of TGCTs represents a …

Context Clinical management of testicular germ cell tumours (GCTs) is hampered by low
sensitivity and specificity of the biomarkers currently in use. Circulating microRNAs (miRs) …

Testicular tumors are the most common tumors in adolescent and young men and germ cell
tumors (TGCTs) account for most of all testicular cancers. Increasing incidence of TGCTs …

Background Clinical management of germ cell tumours (GCTs) relies on monitoring of
serum tumour markers. However, the markers α-fetoprotein (AFP), the β-subunit of human …

Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …

Testicular germ cell tumours (GCTs) are the most common malignancy occurring in young
adult men and the incidence of these tumours is increasing. Current research priorities in …

Extragonadal germ cell tumors (EGGCTs) are uncommon neoplasms, which arise in
anatomical locations other than gonads. The pathogenesis of these neoplasms is still poorly …