Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts,
play a critical role in the compartmentalization of signaling pathways. Physical segregation …

Lipid rafts are tightly packed, cholesterol-and sphingolipid-enriched microdomains within the
plasma membrane that play important roles in many pathophysiologic processes. Rafts have …

Cell signaling does not apparently occur randomly over the cell surface, but it seems to be
integrated very often into cholesterol-rich membrane domains, termed lipid rafts. Membrane …

Cholesterol is a lipid molecule that plays an essential role in a number of biological
processes, both physiological and pathological. It is an essential structural constituent of cell …

In addition to the traditional treatments of cancer and cancer prevention, the use of natural
compounds, especially those found in food, should be considered. To clarify if resveratrol …

Plant-derived polyphenolic compounds, such as the stilbene resveratrol (trans-3, 4′, 5-
trihydroxystilbene), have been identified as potent anti-cancer agents. Extensive in vitro …

A plant kingdom is considered as a gold mine for the discovery of many biologically active
substances with therapeutic values. Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally …

Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene; RV), a dietary constituent found in grapes
and wine, exerts a wide variety of pharmacological activities. Because the grape skins are …