Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

Protein arginine methyltransferase 1, a major regulator of biological processes

SRN Sudhakar, SN Khan, A Clark… - … and Cell Biology, 2023 - cdnsciencepub.com
Protein arginine methyltransferase 1 (PRMT1) is a major type I arginine methyltransferase
that catalyzes the formation of monomethyl and asymmetric dimethylarginine in protein …

Identification of Breast Cancer Metastasis Markers from Gene Expression Profiles Using Machine Learning Approaches

J Jung, S Yoo - Genes, 2023 - mdpi.com
Cancer metastasis accounts for approximately 90% of cancer deaths, and elucidating
markers in metastasis is the first step in its prevention. To characterize metastasis marker …

Competing endogenous RNA (ceRNA) networks and splicing switches in cervical cancer: HPV oncogenesis, clinical significance and therapeutic opportunities

A Basera, R Hull, D Demetriou, DO Bates… - Microorganisms, 2022 - mdpi.com
Cervical cancer (CC) is the primary cause of female cancer fatalities in low-middle-income
countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in …

High Intratumoral i-tRF-GlyGCC Expression Predicts Short-Term Relapse and Poor Overall Survival of Colorectal Cancer Patients, Independent of the TNM Stage

S Christodoulou, K Katsaraki, P Vassiliu, N Danias… - Biomedicines, 2023 - mdpi.com
Colorectal cancer (CRC), one of the most prevalent types of cancer, requires the discovery
of new tumor biomarkers for accurate patient prognosis. In this work, the prognostic value of …

Exploring the molecular biomarker utility of circCCT3 in multiple myeloma: A favorable prognostic indicator, particularly for R‐ISS II patients

M Papatsirou, CK Kontos… - …, 2024 - Wiley Online Library
Circular RNAs (circRNAs) are associated with the pathobiology of multiple myeloma (MM).
Recent findings regarding circCCT3 support its involvement in the development and …

Discovery and Comprehensive Characterization of Novel Circular RNAs of the Apoptosis-Related BOK Gene in Human Ovarian and Prostate Cancer Cells, Using …

CK Kontos, D Hadjichambi, M Papatsirou, P Karousi… - Non-coding RNA, 2023 - mdpi.com
CircRNAs have become a novel scientific research hotspot, and an increasing number of
studies have shed light on their involvement in malignant progression. Prompted by the …

MicroRNA-675-5p Overexpression Is an Independent Prognostic Molecular Biomarker of Short-Term Relapse and Poor Overall Survival in Colorectal Cancer

S Christodoulou, CD Sotiropoulou, P Vassiliu… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is the main cause of cancer-related deaths globally, highlighting
the importance of accurate biomarkers for early detection and accurate prognosis …

Beyond traditional translation: ncRNA derived peptides as modulators of tumor behaviors

K Wen, X Chen, J Gu, Z Chen, Z Wang - Journal of Biomedical Science, 2024 - Springer
Within the intricate tapestry of molecular research, noncoding RNAs (ncRNAs) were
historically overshadowed by a pervasive presumption of their inability to encode proteins or …

[HTML][HTML] Targeted nanopore sequencing for the identification of novel PRMT1 circRNAs unveils a diverse transcriptional profile of this gene in breast cancer cells

M Papatsirou, A Scorilas, DC Sideris… - Genes & …, 2024 - ncbi.nlm.nih.gov
Long-read sequencing with nanopore technology has been widely utilized for the
identification of the full-length sequence of RNA molecules. 1 It is especially suitable for the …