The fibroblast growth factor (FGF) family, which comprises 22 structurally related proteins,
plays diverse roles in cell proliferation, differentiation, development, and metabolism. Among …

Metabolic syndrome is a complex metabolic disorder that often clinically manifests as
obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension. With the …

Periodontitis is an infectious disease caused by an imbalance between the local microbiota
and host immune response. Epidemiologically, periodontitis is closely related to the …

Beta klotho (KLB) is a fundamental component in fibroblast growth factor receptor (FGFR)
signaling as it serves as an obligatory coreceptor for the endocrine hormones fibroblast …

Glucose and lipid metabolism dysregulation in skeletal muscle contributes to the
development of metabolic disorders. The efficacy of fucoxanthin in alleviating lipid metabolic …

Fibrotic diseases affect multiple organs and are associated with morbidity and mortality. To
examine organ-specific and shared biologic mechanisms that underlie fibrosis in different …

Background The beneficial effects of fibroblast growth factor 21 (FGF21) and sodium
butyrate (NaB) on protection against cholestasis-induced liver fibrosis are not well known …

More and more evidence shows that metabolic reprogramming is closely related to the
occurrence of AD. The metabolic conversion of oxidative phosphorylation into glycolysis will …

Abstract Fibroblast growth factor 21 (FGF21) was originally identified as an important
metabolic regulator which plays a crucial physiological role in regulating a variety of …

Fibroblast growth factor (FGF) 21 is an endocrine hormone that signals to multiple tissues to
regulate metabolism. FGF21 and another endocrine FGF, FGF15/19, signal to target tissues …