Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings

P Majumdar, A Pati, M Patra, RK Behera… - Chemical …, 2014 - ACS Publications
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …

Recent advances bioactive 1, 2, 4-triazole-3-thiones

ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

Synthesis and biological activity of Schiff and Mannich bases bearing 2, 4-dichloro-5-fluorophenyl moiety

MS Karthikeyan, DJ Prasad, B Poojary, KS Bhat… - Bioorganic & medicinal …, 2006 - Elsevier
A series of 2, 4-dichloro-5-fluorophenyl bearing Mannich base (4 and 5) was prepared from
triazole Schiff bases (3) by aminomethylation with formaldehyde and secondary/substituted …

1, 2, 4-Triazoles: A review of synthetic approaches and the biological activity

S Maddila, R Pagadala… - Letters in Organic …, 2013 - benthamdirect.com
1, 2, 4-Triazoles and their derivatives have a distinct place in the field of medicinal and
pharmaceutical chemistry. These are used as lead compounds for the synthesis of …

Metal based biologically active compounds: Design, synthesis, and antibacterial/antifungal/cytotoxic properties of triazole-derived Schiff bases and their oxovanadium …

ZH Chohan, SH Sumrra, MH Youssoufi… - European journal of …, 2010 - Elsevier
A new series of oxovanadium (IV) complexes have been designed and synthesized with a
new class of triazole Schiff bases derived from the reaction of 3, 5-diamino-1, 2, 4-triazole …

Synthesis and antimicrobial activity evaluation of new 1, 2, 4-triazoles and 1, 3, 4-thiadiazoles bearing imidazo [2, 1-b] thiazole moiety

NU Güzeldemirci, Ö Küçükbasmacı - European journal of medicinal …, 2010 - Elsevier
A series of 4-alkyl/aryl-2, 4-dihydro-5-((6-(4-bromophenyl) imidazo [2, 1-b] thiazol-3-yl)
methyl)-3H-1, 2, 4-triazole-3-thiones (3a–i) and 2-alkyl/arylamino-5-((6-(4-bromophenyl) …

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy) methyl]-4-alkyl/aryl-2, 4-dihydro-3H-1, 2, 4-triazole-3-thiones and evaluation as …

İ Küçükgüzel, E Tatar, ŞG Küçükgüzel, S Rollas… - European journal of …, 2008 - Elsevier
As a continuation of our previous efforts on N-alkyl/aryl-N′-[4-(4-alkyl/aryl-2, 4-dihydro-3H-
1, 2, 4-triazole-3-thione-5-yl) phenyl] thioureas 1–19 and N-alkyl/aryl-N′-[4-(3-aralkylthio-4 …

Synthesis of benzotriazoles derivatives and their dual potential as α-amylase and α-glucosidase inhibitors in vitro: Structure-activity relationship, molecular docking …

S Hameed, F Seraj, R Rafique, S Chigurupati… - European Journal of …, 2019 - Elsevier
Abstract Benzotriazoles (4–6) were synthesized which were further reacted with different
substituted benzoic acids and phenacyl bromides to synthesize benzotriazole derivatives (7 …

Recent developments on triazole nucleus in anticonvulsant compounds: a review

MX Song, XQ Deng - Journal of enzyme inhibition and medicinal …, 2018 - Taylor & Francis
Epilepsy is one of the common diseases seriously threatening life and health of human.
More than 50 million people are suffering from this condition and anticonvulsant agents are …

Synthesis, characterization, and analgesic activity of novel schiff base of isatin derivatives

RP Chinnasamy, R Sundararajan… - Journal of advanced …, 2010 - journals.lww.com
In the present study, a series of novel Schiff bases of isatin [5a-5l] were synthesized by
condensation of imesatin with different aromatic aldehydes. The imesatins were synthesized …