Selecting the appropriate formulation and solubility-enabling technology for poorly water
soluble drugs is an essential element in the development of formulations for paediatric …

Objective The aim of this prospective randomized double-blind study is to evaluate whether
oral dexmedetomidine (DEX) premedication could increase sedation in order to reduce …

Effective management of pain and anxiety in pediatric emergency room is crucial for
ensuring both the physical and emotional well-being of young patients. Analgosedation, a …

Background: Most preschool children are distressed during anesthesia induction. While
current pharmacological methods are useful, there is a need for further optimization to an …

目的: 比较咪达唑仑口服溶液与右美托咪定喷鼻对儿童术前焦虑的影响. 方法: 选取2022 年6~ 12
月在我院拟行择期手术患儿90 例, 采用随机数字表法分为咪达唑仑口服溶液组 …

Purpose The optimal sedative regime that provides the greatest comfort and the lowest risk
for procedural sedation in young children remains to be determined. The aim of this …

Harmonized methodologies are urgently required for the taste evaluation of novel pediatric
medicines. This study utilized in vitro, in vivo and clinical data to evaluate the palatability of a …

Background Oral administration of midazolam syrup is one of the most favorable methods of
premedication, the optimal dose of midazolam and midazolam with S-ketamine for …

Objective The objective of this study was to assess the efficacy and tolerability of intranasal
midazolam (in-MDZ) administration for antiseizure treatment in adults. Methods Embase and …

Background Radial artery cannulation can be challenging, particularly for inexperienced
providers. This study aimed to compare the success rates of resident physicians performing …