Abstract Microaerophilic, Gram-negative Campylobacter jejuni is the causative agent of
campylobacteriosis, the most common bacterial gastrointestinal infection worldwide …

The tuberactinomycins are a family of cyclic peptide ribosome-targeting antibiotics with a
long history of use as essential second-line treatments for drug-resistant tuberculosis …

Listeria monocytogenes (Lm) is a foodborne pathogen that can cause severe human illness.
Standard control measures for restricting bacterial growth, such as refrigeration, are often …

Changes in bacterial ribosomal RNA (rRNA) methylation status can alter the activity of
diverse groups of ribosome-targeting antibiotics. These modifications are typically …

Campylobacter jejuni is a leading cause of human gastrointestinal disease and small
ruminant abortions in the United States. The recent emergence of a highly virulent …

Numerous bacterial pathogens express an ortholog of the enzyme TlyA, which is an rRNA
2′-O-methyltransferase associated with resistance to cyclic peptide antibiotics such as …

Campylobacter jejuni is a bacterial pathogen that is generally acquired as a zoonotic
infection from poultry and animals. Adhesion of C. jejuni to human colorectal epithelial cells …

Helicobacter pylori is a human-specific Gram-negative pathogenic bacterium which
colonizes the gastric mucosal layer in the stomach causing diseases such as peptic ulcer …

Background TlyA proteins are expressed in a variety of pathogenic bacteria and possess
dual hemolytic and ribosomal RNA methyltransferase functions. While the mechanism of …

Campylobacter jejuni is one of the leading causes of human bacterial gastroenteritis, and
campylobacteriosis in sheep. The genetic diversity of this organism, the potential for multiple …