The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

There is an impression in the literature that schizophrenia is associated with increased
inflammation, including abnormal blood levels of the acute phase reactant C-reactive protein …

The inflammatory hypothesis of schizophrenia (SZ) posits that inflammatory processes and
neural–immune interactions are involved in its pathogenesis, and may underpin some of its …

The evidence to date, coupled with advances in immunology and genetics has afforded the
field an unparalleled opportunity to investigate the hypothesis that a subset of patients with …

Objective: Whilst dopaminergic dysfunction remains a necessary component involved in the
pathogenesis of schizophrenia, our current pharmacological armoury of dopamine …

At present there are strong indications of a shared vulnerability factor for schizophrenia (SZ),
diabetes and the metabolic syndrome (metS). In this study we focus on an aberrantly …

Background Patients with schizophrenia display peripheral inflammation but the impact of
illness phase is not clear. Our meta-analysis investigated the difference in CRP levels …

Clozapine is an effective antipsychotic medication used for treatment‐resistant
schizophrenia. However, it is underutilized due to rigorous hematologic monitoring …

As the global burden of mortality from COVID-19 continues to rise, an understanding of who
is most at risk of adverse outcomes is of paramount importance. Pre-existing …

The longstanding investigation of immune system abnormalities, including inflammation, in
schizophrenia has tremendous renewed interest as an area of research. Presently, the field …