Molecular tests potentially improving HPV screening and genotyping for cervical cancer prevention
A Gradíssimo, RD Burk - Expert Review of Molecular Diagnostics, 2017 - Taylor & Francis
ABSTRACT Introduction: Human papillomavirus (HPV)-related cancers can be averted by
type-specific vaccination (primary prevention) and/or through detection and ablation of …
type-specific vaccination (primary prevention) and/or through detection and ablation of …
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
Human papillomavirus (HPV) integration is a key genetic event in cervical carcinogenesis.
By conducting whole-genome sequencing and high-throughput viral integration detection …
By conducting whole-genome sequencing and high-throughput viral integration detection …
[HTML][HTML] Next generation sequencing and its applications in HPVassociated cancers
M Tuna, CI Amos - Oncotarget, 2017 - ncbi.nlm.nih.gov
Approximately 18% of all human cancers have a viral etiology, and human papillomavirus
(HPV) has been identified as one of the most prevalent viruses that plays causative role in …
(HPV) has been identified as one of the most prevalent viruses that plays causative role in …
Circulating cell‐free HPV DNA is a strong marker for disease severity in cervical cancer
S Bønløkke, T Steiniche, BS Sorensen… - Molecular …, 2024 - Wiley Online Library
For cervical cancer (CC), circulating cell‐free HPV DNA (ccfHPV) may establish disease
severity. Furthermore, HPV integration has been correlated to viral load and survival. In this …
severity. Furthermore, HPV integration has been correlated to viral load and survival. In this …
Genome‐wide profiling of human papillomavirus DNA integration into human genome and its influence on PD‐L1 expression in chinese uygur cervical cancer women
F Yang-Chun, W Sen-Yu, Z Yuan… - Journal of Immunology …, 2020 - Wiley Online Library
Background. The Uygur is the fifth most populous ethnic group in China. Compared to other
Chinese population, cervical cancer in them had high incidence, and HPV infection also was …
Chinese population, cervical cancer in them had high incidence, and HPV infection also was …
HPV-16 E2/E6 and POU5F1B as biomarkers to determine cervical high-grade squamous lesions and more
L Chen, B Dong, H Gao, H Xue, D Pan… - Journal of Inflammation …, 2020 - Taylor & Francis
Purpose: Human papillomavirus-16 (HPV-16) is the most carcinogenic HPV genotype. This
study aimed to evaluate the clinical value of POU5F1B and HPV-16-E2/E6 by cervical …
study aimed to evaluate the clinical value of POU5F1B and HPV-16-E2/E6 by cervical …
Genetic variability in the E6, E7, and L1 genes of human papillomavirus types 16 and 18 among women in Saudi Arabia
M Alsanea, A Alsaleh, D Obeid, F Alhadeq, B Alahideb… - Viruses, 2022 - mdpi.com
Cervical cancer is the eighth most frequent cancer in Saudi Arabia, and most cases are
associated with human papillomavirus (HPV) types 16 and 18. HPV-induced carcinogenesis …
associated with human papillomavirus (HPV) types 16 and 18. HPV-induced carcinogenesis …
Long-read sequencing reveals the structural complexity of genomic integration of HPV DNA in cervical cancer cell lines
Z Wang, C Liu, W Liu, X Lv, T Hu, F Yang, W Yang… - BMC genomics, 2024 - Springer
Background Cervical cancer (CC) causes more than 311,000 deaths annually worldwide.
The integration of human papillomavirus (HPV) is a crucial genetic event that contributes to …
The integration of human papillomavirus (HPV) is a crucial genetic event that contributes to …
Identification of reliable biomarkers of human papillomavirus 16 methylation in cervical lesions based on integration status using high-resolution melting analysis
L Liu, C Ying, Z Zhao, L Sui, X Zhang, C Qian… - Clinical …, 2018 - Springer
Background The dynamic methylation of human papillomavirus (HPV) 16 DNA is thought to
be associated with the progression of cervical lesions. Previous studies that did not consider …
be associated with the progression of cervical lesions. Previous studies that did not consider …
Human papillomavirus (HPV) integration signature in cervical lesions: identification of MACROD2 gene as HPV hot spot integration site
J Zhao, W Zheng, L Wang, H Jiang, X Wang… - Archives of Gynecology …, 2023 - Springer
Background High-risk HPV is clearly associated with cervical cancer. Integration of HPV
DNA into the host genome is considered a key event in driving cervical carcinogenesis …
DNA into the host genome is considered a key event in driving cervical carcinogenesis …