[HTML][HTML] New opportunities and challenges of natural products research: When target identification meets single-cell multiomics

Y Zhu, Z Ouyang, H Du, M Wang, J Wang, H Sun… - … Pharmaceutica Sinica B, 2022 - Elsevier
Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …

Advances in drug development for hepatocellular carcinoma: clinical trials and potential therapeutic targets

XY Luo, KM Wu, XX He - Journal of Experimental & Clinical Cancer …, 2021 - Springer
Although hepatocellular carcinoma (HCC) is one of the deadliest health burdens worldwide,
few drugs are available for its clinical treatment. However, in recent years, major …

Guidelines for the diagnosis and treatment of primary liver cancer (2022 edition)

J Zhou, H Sun, Z Wang, W Cong, M Zeng, W Zhou… - Liver Cancer, 2023 - karger.com
Background: Primary liver cancer, of which around 75–85% is hepatocellular carcinoma in
China, is the fourth most common malignancy and the second leading cause of tumor …

[HTML][HTML] Standard for diagnosis and treatment of primary liver cancer (2022 edition)

General Office of National Health Commission - 临床肝胆病杂志, 2022 - lcgdbzz.com
Standard for diagnosis and treatment of primary liver cancer (2022 edition) 中文|English ISSN
1001-5256 (Print) ISSN 2097-3497 (Online) CN 22-1108/R Home About Journal 1.Journal …

Treatment for liver cancer: From sorafenib to natural products

S Man, C Luo, M Yan, G Zhao, L Ma, W Gao - European journal of …, 2021 - Elsevier
Liver cancer most commonly develops in patients with chronic liver disease, the etiology of
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …

IL-6/STAT3 is a promising therapeutic target for hepatocellular carcinoma

J Xu, H Lin, G Wu, M Zhu, M Li - Frontiers in oncology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common malignant tumor of which the occurrence and
development, the tumorigenicity of HCC is involving in multistep and multifactor interactions …

Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma

Y Lu, Y Gao, H Yang, Y Hu, X Li - Military Medical Research, 2022 - Springer
Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical
resection, transplantation, radiofrequency ablation, and chemotherapy are unsatisfactory …

Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways

P Kubatka, A Mazurakova, M Samec, L Koklesova… - Epma Journal, 2021 - Springer
Inflammation is an essential pillar of the immune defense. On the other hand, chronic
inflammation is considered a hallmark of cancer initiation and progression. Chronic …

Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER–ERK–NF-κB signaling pathway

Z Yu, G Su, L Zhang, G Liu, Y Zhou, S Fang, Q Zhang… - Molecular …, 2022 - Springer
Background Activated microglia play a key role in initiating the inflammatory cascade
following ischemic stroke and exert proinflammatory or anti-inflammatory effects, depending …

Icaritin: A phytomolecule with enormous pharmacological values

NT Huong, NT Son - Phytochemistry, 2023 - Elsevier
Pharmacological studies on flavonoids have always drawn much interest for many years.
Icaritin (ICT), a representative flavone containing an 8-prenyl group, is a principal compound …