With increasing life span as afforded by nutritional, technological, and therapeutic
advancements during the last century, cardiac diseases have moved to the top of morbidity …

Acute myocardial infarction is the leading cause of morbidity and mortality in the adult
population of developed and developing nations. Although the prompt restoration of …

Overnutrition and insulin resistance are especially prominent risk factors for the
development of cardiac diastolic dysfunction in females. We recently reported that …

Gallic acid, a type of phenolic acid, has been shown to have beneficial effects in
inflammation, vascular calcification, and metabolic diseases. The present study was aimed …

Fibrosis is a pathological repair process common among organs, that responds to tissue
damage by replacement with non-functional connective tissue. Despite the widespread …

Angiotensin II (Ang II) modulates vasomotor tone, cell growth, and extracellular matrix
deposition. This study analyzed the effect of atorvastatin in the possible alterations induced …

Angiotensin II is a powerful mediator to induce cardiac remodeling and fibrosis.
Transforming growth factor-β1 (TGF-β1) and extracellular signal-regulated kinase (ERK) …

Transforming growth factor β (TGF-β) is a multifunctional cytokine that is synthesized by
many types of cells and regulates the cell cycle. Increasing evidence has led to TGF-β …

Radiation-induced heart injury is one of the major side effects of radiotherapy for thoracic
malignancies. Previous studies have shown that radiotherapy induced myocardial fibrosis …

Importance Adhesion-related complications (ARCs), including small-bowel obstruction, are
common complications of intra-abdominal surgery. Statins, which have antifibrotic …