Extracellular Vesicles in Trypanosoma cruzi Infection: Immunomodulatory Effects and Future Perspectives as Potential Control Tools against Chagas Disease

N Cortes-Serra, M Gualdron-Lopez… - Journal of …, 2022 - Wiley Online Library
Chagas disease, caused by the protozoa parasite Trypanosoma cruzi, is a neglected
tropical disease and a major public health problem affecting more than 6 million people …

Transforming parasites into their own foes: parasitic extracellular vesicles as a vaccine platform

D Alfandari, S Cadury, MI Morandi… - Trends in …, 2023 - cell.com
Parasitic diseases continue to afflict millions of people globally. However, traditional vaccine
development strategies are often difficult to apply to parasites, leaving an immense unmet …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

Dogs with canine visceral leishmaniasis have a boost of extracellular vesicles and miR‐21‐5p up‐expression

AB da Cruz, FM Carneiro, MM Maia… - Parasite …, 2023 - Wiley Online Library
This retrospective cohort study analysed extracellular vesicles (EVs) and microRNAs
(miRNAs) excreted in canine sera from dogs with canine visceral leishmaniasis (CanVL). A …

Extracellular Vesicles: Potential Role in Remote Signaling and Inflammation in Trypanosoma cruzi-Triggered Disease

L Dantas-Pereira, R Menna-Barreto… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) act as cell communicators and immune response modulators
and may be employed as disease biomarkers and drug delivery systems. In infectious …

Protozoa-Derived Extracellular Vesicles on Intercellular Communication with Special Emphasis on Giardia lamblia

B Ferreira, Á Lourenço, MC Sousa - Microorganisms, 2022 - mdpi.com
Parasitic diseases are an important worldwide problem threatening human health and affect
millions of people. Acute diarrhea, intestinal bleeding, malabsorption of nutrients and …

Plasma-derived exosomal miRNA as potential biomarker for diagnosis and prognosis of vector-borne diseases: A review

G Venkatesan, WS Wan Ab Rahman… - Frontiers in …, 2023 - frontiersin.org
Early disease diagnosis is critical for better management and treatment outcome of patients.
Therefore, diagnostic methods should ideally be accurate, consistent, easy to perform at low …

Isolation and molecular characterization of circulating extracellular vesicles from blood of chronic Chagas disease patients

RP Madeira, P Meneghetti, LA de Barros… - Cell biology …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer envelopes that encase several types of
molecules. Their contents mostly reflect their cell origin and possible targets at other …

Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases

AAS Pinheiro, AC Torrecilhas… - Journal of …, 2024 - Wiley Online Library
Parasitic diseases have a significant impact on human and animal health, representing a
major hazard to the public and causing economic and health damage worldwide …

Extracellular vesicles in the context of chagas disease-A systematic review

EM Garcez, N Gomes, AS Moraes, R Pogue… - Acta Tropica, 2023 - Elsevier
Extracellular vesicle (EVs) traffic is considered an important cellular communication process
between cells that can be part of a single organism or belong to different living beings. The …