Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement

M Eslam, N Alkhouri, P Vajro, U Baumann… - The Lancet …, 2021 - thelancet.com
The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …

NASH in lean individuals

R Younes, E Bugianesi - Seminars in liver disease, 2019 - thieme-connect.com
Nonalcoholic fatty liver disease (NAFLD) is generally associated with obesity and the related
comorbidities but it can also develop in subjects with a body mass index (BMI) within the …

Nonalcoholic fatty liver disease in children: unique considerations and challenges

D Goldner, JE Lavine - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence in concert with the
global epidemic of obesity and is being diagnosed at increasingly younger ages. The …

Emerging role of genomic analysis in clinical evaluation of lean individuals with NAFLD

S Vilarinho, V Ajmera, M Zheng, R Loomba - Hepatology, 2021 - journals.lww.com
Results We found that ALCDs are critical regions of the human genome that are located on
all human chromosomes, preferentially in intronic regions of the oncogenes and other …

A review of non‐alcoholic fatty liver disease in non‐obese and lean individuals

M Ahadi, K Molooghi, N Masoudifar… - Journal of …, 2021 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is one of the most common causes of hepatic
disorders. It represents a wide range of chronic liver diseases in patients with no history of …

Epidemiology of pediatric nonalcoholic fatty liver disease

LY Elizabeth, JB Schwimmer - Clinical Liver Disease, 2021 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD), defined as abnormal hepatic accumulation of
macrovesicular fat in the absence of other etiologies, such as infection, autoimmune …

Lean NAFLD: an underrecognized and challenging disorder in medicine

S Maier, A Wieland, M Cree-Green, K Nadeau… - Reviews in Endocrine …, 2021 - Springer
Abstract Classically, Non-Alcoholic Fatty Liver Disease (NAFLD) has been thought to be
driven by excessive weight gain and obesity. The overall greater awareness of this disorder …

From Nonalcoholic Fatty Liver Disease (NAFLD) to Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)—New Terminology in Pediatric Patients as a Step …

M Flisiak-Jackiewicz, A Bobrus-Chociej… - Journal of clinical …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
world, which predispose to more serious hepatic conditions. It ranges from simple liver …

Epidemiology and prevalence of lean nonalcoholic fatty liver disease and associated cirrhosis, hepatocellular carcinoma, and cardiovascular outcomes in the United …

A Almomani, P Kumar, S Onwuzo… - Journal of …, 2023 - Wiley Online Library
Backgrounds Nonalcoholic fatty liver disease (NAFLD) is linked to obesity and metabolic
syndrome conditions. However, a subset of NAFLD patients express a normal or low body …

Clinical epidemiology of non-alcoholic fatty liver disease in children and adolescents. The LiverKids: Study protocol

C Chacón, I Arteaga, A Martínez-Escudé, I Ruiz Rojano… - Plos one, 2023 - journals.plos.org
Background Non-alcoholic fatty liver disease (NAFLD) is rapidly increasing alongside
overweight and obesity, not only in adults but also in children and adolescents. It is unknown …