4-Thiazolidinone–A biologically active scaffold

A Verma, SK Saraf - European journal of medicinal chemistry, 2008 - Elsevier
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[PDF][PDF] Exploring potential of 4-thiazolidinone: a brief review

M Abhinit, M Ghodke, NA Pratima - Int J Pharm Pharm Sci, 2009 - researchgate.net
Thiazolidinone, a saturated form of thiazole with carbonyl group on fourth carbon, has been
considered as a magic moiety (wonder nucleus) which posses almost all types of biological …

Synthesis of new thiazole clubbed imidazo [2, 1-b] thiazole hybrid as antimycobacterial agents

HK Mahmoud, AR Sayed, MM Abdel-Aziz… - Medicinal …, 2022 - ingentaconnect.com
Aims: The study aims to synthesize bioactive hybrid pharmacophores (thiazole ring and
imidazo [2, 1-b] thiazole system) by incorporating them into one biological assessment …

Synthesis and Antituberculosis Activity of Cycloalkylidenehydrazide and 4-Aza-1-thiaspiro [4.5] decan-3-one Derivatives of Imidazo [2][1-b] thiazole

N Ulusoy - Arzneimittelforschung, 2002 - thieme-connect.com
New N 2-cycloalkylidene-(6-phenyl/4-chlorophenylimidazo [2, 1-b] thiazol-3-yl) acetic acid
hydrazides (2a-h and 3a-b) were synthesized by reacting (6-phenyl/4-chlorophenylimidazo …

Synthesis of some biologically active pyrazole, thiazolidinone, and azetidinone derivatives

RB Pawar, VV Mulwad - Chemistry of Heterocyclic Compounds, 2004 - Springer
Pyrazole, thiazolidinone, and azetidinone derivatives were synthesized from chalcones of 4-
hydroxycoumarin. The structures of all the synthesized compounds were confirmed on the …

Synthesis of unsymmetrical bis-heterocycles containing the imidazo [2, 1-b] thiazole framework and their benzo [d] fused analogues by an acid-free Groebke …

KG Kishore, A Islas-Jácome, A Rentería-Gómez… - Tetrahedron …, 2016 - Elsevier
A series of twenty three novel unsymmetrical bis-heterocycles having either imidazo [2, 1-b]
thiazole or benzo [d] imidazo [2, 1-b] thiazole frameworks bound with chromone, quinoline …

Macromolecular drug targets in cancer treatment and thiosemicarbazides as anticancer agents

Ŧ Güniz Küçükgüzel… - Anti-Cancer Agents in …, 2016 - benthamdirect.com
Cancer is known as abnormal cell division and consisting of a group of diseases on various
organ tissues. Many therapies are available in cancer treatment such as chemotherapy …

Synthesis of S-alkylated oxadiazole bearing imidazo [2, 1-b] thiazole derivatives targeting breast cancer: In vitro cytotoxic evaluation and in vivo radioactive tracing …

ER Mohammed, MAF Ezzat, EM Seif, BM Essa… - Bioorganic …, 2024 - Elsevier
Breast cancer is the most common invasive cancer diagnosed in women, accounting for
most cancer-related fatalities globally. Numerous investigations have revealed that breast …

Synthesis and biological evaluation of some innovative coumarin derivatives containing thiazolidin-4-one ring

CK RamaGanesh, YD Bodke, KB Venkatesh - 2010 - nopr.niscpr.res.in
The reaction of ethyl 2-oxo-2H-chromene-3-carboxylate with hydrazine followed by
condensation of the resulting hydrazone with different aromatic aldehydes give the …

Synthesis of some new 6-methylimid azo [2, 1-b] thiazole-5-carbohydrazide derivatives and their antimicrobial activities

F Ur, N Cesur, S Birteksoez, G Oetuek - Arzneimittelforschung, 2004 - thieme-connect.com
In this study, 14 new compounds having 6-methyl-N 2-(alkylidene/cycloalkylidene) imidazo
[2, 1-b] thiazole-5-carbohydrazide (3a-g), 3-[[(6-methylimid-azo [2, 1-b] thiazole-5-yl) …