Apart from the typical motor symptoms, Parkinson's disease is characterized by a wide range of different non-motor symptoms, which are highly prevalent in all stages of the disease and …
V Czernecki, M Schüpbach, S Yaici… - … : official journal of the …, 2008 - Wiley Online Library
To evaluate the effects of the dopamine D2‐D3 agonist ropinirole in patients who developed apathy after complete withdrawal from dopaminergic medication following successful …
Parkinson's disease is a neurodegenerative disorder involving the basal ganglia that results in a host of motor and cognitive deficits. Dopamine-replacement therapy ameliorates some …
M Sobiech, J Giebułtowicz, M Woźnica, I Jaworski… - Microchemical …, 2022 - Elsevier
In this paper, the theoretical models of the molecularly imprinted polymer surface microenvironment were investigated. S-Pramipexole was used as a model drug and its …
M Alajarin, J Cabrera, D Bautista… - The Journal of …, 2024 - ACS Publications
4-Alkenyl-2-dialkylaminothiazoles act as in–out dienes in [4+ 2] cycloaddition reactions with nitroalkenes, furnishing 2-amino-6-nitro-4, 5, 6, 7-tetrahydrobenzothiazoles in moderate to …
MA Roy, M Doiron, J Talon-Croteau… - Canadian Journal of …, 2018 - cambridge.org
Objective: This study aimed to systematically review the effects of currently prescribed antiparkinson medication on cognition in patients with mild-to-moderate Parkinson's disease …
Subtle cognitive impairment can be detected in early Parkinson's disease (PD). In a consecutive series of de novo, drug-naive PD patients, we applied stepwise regression …
R Constantinescu - Neuropsychiatric disease and treatment, 2008 - Taylor & Francis
Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson's disease (PD). This review addresses the literature concerning pramipexole's …
RL Drijgers, FRJ Verhey, G Tissingh… - Journal of the …, 2012 - Elsevier
In Parkinson's disease (PD) reduced dopaminergic activity in the mesocorticolimbic pathway is implied in the pathophysiology of several non-motor symptoms related to mood …