Deep learning-based real-time detection of neurons in brain slices for in vitro physiology

MC Yip, MM Gonzalez, CR Valenta, MJM Rowan… - Scientific reports, 2021 - nature.com
A common electrophysiology technique used in neuroscience is patch clamp: a method in
which a glass pipette electrode facilitates single cell electrical recordings from neurons …

Method for rapid enzymatic cleaning for reuse of patch clamp pipettes: Increasing throughput by eliminating manual pipette replacement between patch clamp …

CR Landry, MC Yip, I Kolb, WA Stoy, MM Gonzalez… - Bio …, 2021 - bio-protocol.org
The whole-cell patch-clamp method is a gold standard for single-cell analysis of electrical
activity, cellular morphology, and gene expression. Prior to our discovery that patch-clamp …

Single neuron recording: progress towards high-throughput analysis

A Alegria, A Joshi, J O'Brien… - Bioelectronics in …, 2020 - Taylor & Francis
Since its development in the late 70s and early 80s by Nobel laureates Erwin Neher and
Bert Sakmann [1], patch clamping has been the gold standard single-cell electrophysiology …

Universal robot for automated microinjection with applications in transgenesis and cryopreservation

AS Joshi - 2023 - search.proquest.com
Microinjection is the process of injecting a small amount of solution into biological organisms
at a microscopic level using a glass micropipette. It is a widely utilized technique with a wide …