Macrophages can be affected by a variety of factors to change their phenotype and thus
affect their function. Activated macrophages are usually divided into two categories, M1-like …

Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Activated macrophages switch from oxidative phosphorylation to aerobic glycolysis, similar
to the Warburg effect, presenting a potential therapeutic target in inflammatory disease. The …

Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is a
chronic relapsing inflammatory disease of the gastrointestinal tract that closely related to …

Restoring immune balance by targeting macrophage polarization is a potentially valuable
therapeutic strategy for ulcerative colitis (UC). Dioscin is a steroidal saponin with potent anti …

Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue
microenvironment. Currently, little is known about how the intrinsic regulators modulate …

Tumor-associated myeloid cells maintain immunosuppressive microenvironments within
tumors. Identification of myeloid-specific receptors to modulate tumor-associated …

Macrophages are highly plastic in different tissues and can differentiate into functional
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …

Obesity is a nutritional disorder resulting from a chronic imbalance between energy intake
and expenditure. This disease is characterized by inflammation in multiple cell types …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …