Applications for preclinical PET/MRI

MS Judenhofer, SR Cherry - Seminars in nuclear medicine, 2013 - Elsevier
Currently, the combination of positron emission tomography (PET) and magnetic resonance
imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its …

Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a …

HJ Cho, E Ackerstaff, S Carlin, ME Lupu, Y Wang… - Neoplasia, 2009 - Elsevier
In vivo knowledge of the spatial distribution of viable, necrotic, and hypoxic areas can
provide prognostic information about the risk of developing metastases and regional …

Preclinical molecular imaging using PET and MRI

G Wolf, N Abolmaali - Molecular Imaging in Oncology, 2012 - Springer
Molecular imaging fundamentally changes the way we look at cancer. Imaging paradigms
are now shifting away from classical morphological measures towards the assessment of …

Preclinical imaging using single track location shear wave elastography: monitoring the progression of murine pancreatic tumor liver metastasis in vivo

R Ahmed, J Ye, SA Gerber, DC Linehan… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
Recently, researchers have discovered the direct impact of the tumor mechanical
environment on the growth, drug uptake and prognosis of tumors. While estimating the …

A robotic system for‐FMISO PET‐guided intratumoral measurements

J Chang, B Wen, P Kazanzides, P Zanzonico… - Medical …, 2009 - Wiley Online Library
An image‐guided robotic system was used to measure the oxygen tension in rodent tumor
xenografts using interstitial probes guided by tumor hypoxia PET images. Rats with diameter …

Exploring the quantitative relationship between metabolism and enzymatic phenotype by physiological modeling of glucose metabolism and lactate oxidation in solid …

Q Wang, P Vaupel, SI Ziegler… - Physics in Medicine & …, 2015 - iopscience.iop.org
Molecular imaging using PET or hyperpolarized MRI can characterize tumor phenotypes by
assessing the related metabolism of certain substrates. However, the interpretation of the …

A carbon-fiber sheet resistor for MR-, CT-, SPECT-, and PET-compatible temperature maintenance in small animals

V Kersemans, S Gilchrist, S Wallington, PD Allen… - …, 2019 - pmc.ncbi.nlm.nih.gov
A magnetic resonance (MR)-, computed tomography (CT)-, single-photon emission
computed tomography (SPECT)-, and positron emission tomography (PET)-compatible …

Comparison of (immuno-) fluorescence data with serial [18F] Fmiso PET/CT imaging for assessment of chronic and acute hypoxia in head and neck cancers

CA Maftei, K Shi, C Bayer, ST Astner… - Radiotherapy and …, 2011 - Elsevier
PURPOSE: Both, acute and chronic hypoxia can have unfavorable impacts on tumor
progression and therapy response. The aim of this study was to optimize a macroscopic …

[HTML][HTML] An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse

V Kersemans, JS Beech, S Gilchrist, P Kinchesh… - Plos one, 2017 - journals.plos.org
Introduction Preclinical CT-guided radiotherapy platforms are increasingly used but the CT
images are characterized by poor soft tissue contrast. The aim of this study was to develop a …

Reverse-contrast imaging and targeted radiation therapy of advanced pancreatic cancer models

DLJ Thorek, RM Kramer, Q Chen, J Jeong… - International Journal of …, 2015 - Elsevier
Purpose To evaluate the feasibility of delivering experimental radiation therapy to tumors in
the mouse pancreas. Imaging and treatment were performed using combined CT (computed …