Neural control of locomotion in human adults involves the generation of a small set of basic
patterned commands directed to the leg muscles. The commands are generated …

The ability to generate and control locomotor movements depends on complex interactions
between many areas of the nervous system, the musculoskeletal system, and the …

How rudimentary movements evolve into sophisticated ones during development remains
unclear. It is often assumed that the primitive patterns of neural control are suppressed …

Key points• The organization of the spinal circuitry responsible for the generation of
locomotor rhythm and control of locomotion in mammals is largely unknown, though several …

To understand the role of trunk muscles in maintenance of dynamic postural equilibrium we
investigate trunk movements during gait initiation and walking, performing trunk kinematics …

Legged locomotion results from a combination of central pattern generating network (CPG)
activity and intralimb and interlimb sensory feedback. Data on the neural basis of interlimb …

Effective quadrupedal locomotion requires a close coordination between the spatially distant
central pattern generators (CPGs) controlling forelimb and hindlimb movements. Using …

Human stepping movements emerge in utero and show several milestones during
development to independent walking. Recently, imaging has become an essential tool for …

Spinal circuits can generate locomotor output in the absence of sensory or descending
input, but the principles of locomotor circuit organization remain unclear. We sought insight …

The identification of biological modules at the systems level often follows top-down
decomposition of a task goal, or bottom-up decomposition of multidimensional data arrays …