Cyclodextrins: Structural, chemical, and physical properties, and applications

BG Poulson, QA Alsulami, A Sharfalddin… - Polysaccharides, 2021 - mdpi.com
Due to their unique structural, physical and chemical properties, cyclodextrins and their
derivatives have been of great interest to scientists and researchers in both academia and …

Comprehensive study on transglycosylation of CGTase from various sources

CH Lim, B Rasti, J Sulistyo, MA Hamid - Heliyon, 2021 - cell.com
Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a
donor to an acceptor, which is usually performed by enzymatic reactions because of their …

Enhanced Synthesis of 2-O-α-d-Glucopyranosyl-l-ascorbic Acid from α-Cyclodextrin by a Highly Disproportionating CGTase

RK Gudiminchi, A Towns, S Varalwar, B Nidetzky - Acs Catalysis, 2016 - ACS Publications
2-O-α-d-Glucopyranosyl-l-ascorbic acid (AA-2G) is an industrially important derivative of
vitamin C [l-ascorbic acid (l-AA)]. A useful synthetic route toward AA-2G is the selective …

Host–guest inclusion complexation of β-cyclodextrin and hecogenin acetate to enhance anti-hyperalgesic effect in an animal model of musculoskeletal pain

JSS Quintans, EWM Pereira, YMBG Carvalho… - Process …, 2017 - Elsevier
Hecogenin acetate (HA), a steroidal acetylated-sapogenin, has an analgesic profile already
assigned, but its low water solubility and short half-life limit its use in chronic conditions. β …

Engineering CGTase to improve synthesis of alkyl glycosides

KZG Ara, JA Linares-Pastén, J Jönsson… - …, 2021 - academic.oup.com
Alkyl glycoside surfactants with elongated carbohydrate chains are useful in different
applications due to their improved biocompatibility. Cyclodextrin glucanotransferases can …

Synthesis of novel oligomeric anionic alkyl glycosides using laccase/TEMPO oxidation and cyclodextrin glucanotransferase (CGTase)‐catalyzed transglycosylation

NTN Ngo, JA Linares‐Pastén, C Grey… - Biotechnology and …, 2021 - Wiley Online Library
Modification of alkyl glycosides, to alter their properties and widen the scope of potential
applications, is of considerable interest. Here, we report the synthesis of new anionic alkyl …

Current advances in obtaining novel cyclodextrin glycosyltransferases for optimizing the synthesis of cyclodextrins

ICB MUNIZ, JB SANTOS, RM de OLIVEIRA… - Process …, 2024 - Elsevier
The cyclodextrins (CDs) market has increased due to their numerous applications,
especially in the food and pharmaceutical industries. The high cost of synthetizing one …

Heterologous expression of cyclodextrin glycosyltransferase from Paenibacillus macerans in Escherichia coli and its application in 2-O-α-D-glucopyranosyl-L …

Y Jiang, J Zhou, R Wu, F Xin, W Zhang, Y Fang, J Ma… - BMC …, 2018 - Springer
Abstract Background Cyclodextrin glucanotransferase (CGTase) can transform L-ascorbic
acid (L-AA, vitamin C) to 2-O-α-D-glucopyranosyl-L-ascorbic acid (AA-2G), which shows …

Synthesis and Properties of Alkyl β-d-Galactopyranoside

G Chen, Z Li, L Chen, S Ji, W Shen - Journal of Surfactants and Detergents, 2016 - Springer
A series of alkyl β-d-galactopyranosides were prepared by the trichloroacetimidate method
with d-galactose and alcohols with different chain lengths as raw materials. Their solubility …

A multi-enzymatic cascade reaction for the synthesis of bioactive C-oligosaccharides

K Xie, Q Zhang, F Ye, J Dai - Chinese Chemical Letters, 2024 - Elsevier
C-Oligosaccharides are rare in nature and possess diverse bioactivities. However, their
chemical synthesis faces many challenges. In this work, enzymatic introduction of C-linked …