Smart approaches to glucose-responsive drug delivery
MJ Webber, DG Anderson - Journal of Drug targeting, 2015 - Taylor & Francis
A grand challenge in the field of “smart” drug delivery has been the quest to create
formulations that can sense glucose and respond by delivering an appropriate dose of …
formulations that can sense glucose and respond by delivering an appropriate dose of …
Environmentally responsive systems for drug delivery
ML Bruschi, FB Borghi-Pangoni… - Recent Patents on …, 2017 - ingentaconnect.com
Background: In recent decades, the development of the environmentally responsive systems
for drug delivery has been well regarded, with enormous potential in different applications …
for drug delivery has been well regarded, with enormous potential in different applications …
Injectable solution at pH 7 comprising at least one basal insulin whose PI is between 5.8 and 8.5
O Soula, G Soula, J Tonnar, A Geissler - US Patent 9,089,476, 2015 - Google Patents
2,387,201 A 10, 1945 Weiner 4,826,818 A 5, 1989 Mori et al. 5,656,722 A 8/1997 Dörschug
6,100,376 A 8/2000 Dörschug 7,226,618 B1 6, 2007 Touraud et al. 7,718,609 B2 5, 2010 …
6,100,376 A 8/2000 Dörschug 7,226,618 B1 6, 2007 Touraud et al. 7,718,609 B2 5, 2010 …
Insulin therapy: going the “smarter” way
S Kalra, A Joshi, G Parmar - Recent Patents on Endocrine …, 2014 - ingentaconnect.com
Insulin pharmacology has evolved from nonhuman source based extraction of insulin, to use
of recombinant technologies for human insulin production, to tailor made synthetic insulin …
of recombinant technologies for human insulin production, to tailor made synthetic insulin …
Trehalose hydrogels for stabilization and delivery of proteins
HD Maynard - US Patent 10,662,295, 2020 - Google Patents
Petrusic, Stojanka, et al.“Synthesis, characterization and drug release properties of
thermosensitive poly (N-isopropylacrylamide) microgels.” Journal of Polymer Research …
thermosensitive poly (N-isopropylacrylamide) microgels.” Journal of Polymer Research …
Injectable solution at pH 7 comprising at least one basal insulin the pi of which is between 5.8 and 8.5 and a substituted co-polyamino acid
O Soula - US Patent 10,335,489, 2019 - Google Patents
2, 387, 201 A 10/1945 Weiner 4, 826, 818 A 5/1989 Mori et al. 5, 656, 722 A 8/1997
Dorschug 6, 100, 376 A 8/2000 Dorschug 6, 384, 016 B1 5/2002 Kaarsholm 7, 226, 618 B1 …
Dorschug 6, 100, 376 A 8/2000 Dorschug 6, 384, 016 B1 5/2002 Kaarsholm 7, 226, 618 B1 …
Aromatic boron-containing compounds and related insulin analogs
M Sachitanand, C Diao, RK Spencer, JJ Steele… - US Patent …, 2024 - Google Patents
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C (= O) C (NC (= O) C
(CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
(CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Glucose responsive insulins
A Mahdavi - US Patent 11,052,133, 2021 - Google Patents
Chu, MKL, et al., In vitro and in vivo testing of glucose responsive insulin-delivery
microdevices in diabetic rats, Lab on a Chip, The Royal Society of Chemistry, 2012, pp …
microdevices in diabetic rats, Lab on a Chip, The Royal Society of Chemistry, 2012, pp …
Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
US11174288B2 - Heparin-binding cationic peptide self-assembling peptide amphiphiles useful
against drug-resistant bacteria - Google Patents US11174288B2 - Heparin-binding cationic …
against drug-resistant bacteria - Google Patents US11174288B2 - Heparin-binding cationic …
Injectable solution at pH 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer
O Soula, R Charvet - US Patent 10,449,256, 2019 - Google Patents
2.387. 201 A 1 ()/1945 Weiner 4,826,818 A 5/1989 Mori et al. 5,656.722 A 8/1997 Dorschug
6,100.376 A 8/2000 Dorschug 6384016 B 1 5/2002 Kaarsholm 7.226. 618 B1 6/2007 …
6,100.376 A 8/2000 Dorschug 6384016 B 1 5/2002 Kaarsholm 7.226. 618 B1 6/2007 …