Exosomes as naturally occurring vehicles for delivery of biopharmaceuticals: insights from drug delivery to clinical perspectives

A Butreddy, N Kommineni, N Dudhipala - Nanomaterials, 2021 - mdpi.com
Exosomes as nanosized vesicles are emerging as drug delivery systems for therapeutics
owing to their natural origin, their ability to mediate intercellular communication, and their …

Hypoxia induced changes of exosome cargo and subsequent biological effects

H Jiang, H Zhao, M Zhang, Y He, X Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Exosomes are small extracellular vesicles that are secreted by almost all types of cells and
exist in almost all extracellular spaces. As an important mediator of intercellular …

Embryo implantation: war in times of love

N Ashary, A Tiwari, D Modi - Endocrinology, 2018 - academic.oup.com
Contrary to widespread belief, the implantation of an embryo for the initiation of pregnancy is
like a battle, in that the embryo uses a variety of coercive tactics to force its acceptance by …

Extracellular vesicle mediated embryo-endometrial cross talk during implantation and in pregnancy

NK Kurian, D Modi - Journal of assisted reproduction and genetics, 2019 - Springer
Extracellular vesicles are lipoproteinaceous membrane-enclosed nanometer-sized
structures produced by cells and are thought to mediate cellular communications. Loaded …

Immune tolerance of embryo implantation and pregnancy: the role of human decidual stromal cell-and embryonic-derived extracellular vesicles

HM Wu, LH Chen, LT Hsu, CH Lai - International Journal of Molecular …, 2022 - mdpi.com
Embryo–endometrial communication plays a critical role in embryo implantation and the
establishment of a successful pregnancy. Successful pregnancy outcomes involve maternal …

Interferon tau-dependent and independent effects of the bovine conceptus on the endometrial transcriptome

DJ Mathew, JM Sánchez, C Passaro… - Biology of …, 2019 - academic.oup.com
This study investigated bovine conceptus-induced modifications to the endometrial
transcriptome related to effects of interferon tau (IFNT), conceptus origin (in vivo vs. in vitro) …

A comparison of blood plasma small extracellular vesicle enrichment strategies for proteomic analysis

NP Turner, P Abeysinghe, KA Kwan Cheung… - Proteomes, 2022 - mdpi.com
Proteomic analysis of small extracellular vesicles (sEVs) poses a significant challenge. A
'gold-standard'method for plasma sEV enrichment for downstream proteomic analysis is yet …

Extracellular vesicles in embryo implantation and disorders of the endometrium

A Mishra, N Ashary, R Sharma… - American Journal of …, 2021 - Wiley Online Library
Implantation of the embryo is a rate‐limiting step for a successful pregnancy, and it requires
an intricate crosstalk between the embryo and the endometrium. Extracellular vesicles (EVs) …

Role of ADAM and ADAMTS disintegrin and metalloproteinases in normal pregnancy and preeclampsia

H Qu, RA Khalil - Biochemical Pharmacology, 2022 - Elsevier
Normal pregnancy (NP) involves intricate processes starting with egg fertilization,
proceeding to embryo implantation, placentation and gestation, and culminating in …

Characterization of urinary exosomal release of aquaporin-1 and-2 after renal ischemia-reperfusion in rats

S Asvapromtada, H Sonoda… - American Journal …, 2018 - journals.physiology.org
Acute kidney injury (AKI) is an important risk factor for the development of chronic kidney
disease (CKD), and an alteration in renal water handling has been observed during the …