[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Decoding the human face: Progress and challenges in understanding the genetics of craniofacial morphology

S Naqvi, H Hoskens, F Wilke… - Annual review of …, 2022 - annualreviews.org
Variations in the form of the human face, which plays a role in our individual identities and
societal interactions, have fascinated scientists and artists alike. Here, we review our current …

Shaping faces: genetic and epigenetic control of craniofacial morphogenesis

L Selleri, FM Rijli - Nature Reviews Genetics, 2023 - nature.com
Differences in facial morphology distinguish vertebrates. Here, Selleri and Rijli discuss
advances in multi-omics and single-cell technologies linking genes, transcriptional networks …

[HTML][HTML] Combining genome-wide association studies highlight novel loci involved in human facial variation

Z Xiong, X Gao, Y Chen, Z Feng, S Pan, H Lu… - Nature …, 2022 - nature.com
Standard genome-wide association studies (GWASs) rely on analyzing a single trait at a
time. However, many human phenotypes are complex and composed by multiple correlated …

[HTML][HTML] Predicting physical appearance from DNA data—Towards genomic solutions

E Pośpiech, P Teisseyre, J Mielniczuk, W Branicki - Genes, 2022 - mdpi.com
The idea of forensic DNA intelligence is to extract from genomic data any information that
can help guide the investigation. The clues to the externally visible phenotype are of …

[HTML][HTML] Super-enhancer associated core regulatory circuits mediate susceptibility to retinoic acid in neuroblastoma cells

RL Gomez, LM Woods, R Ramachandran… - Frontiers in Cell and …, 2022 - frontiersin.org
Neuroblastoma is a pediatric tumour that accounts for more than 15% of cancer-related
deaths in children. High-risk tumours are often difficult to treat, and patients' survival chances …

Forensic DNA phenotyping: Inferring phenotypic traits from crime scene DNA

P Dabas, S Jain, H Khajuria, BP Nayak - Journal of forensic and legal …, 2022 - Elsevier
Abstract Introduction Forensic DNA Phenotyping (FDP) has provided better understanding of
various phenotypic features (eg, height, skin colour, eye colour, structure and shape of scalp …

Advancement in human face prediction using DNA

A Alshehhi, A Almarzooqi, K Alhammadi, N Werghi… - Genes, 2023 - mdpi.com
The rapid improvements in identifying the genetic factors contributing to facial morphology
have enabled the early identification of craniofacial syndromes. Similarly, this technology …

[HTML][HTML] PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits

D Liu, HJ Ban, AM El Sergani, MK Lee, JT Hecht… - Frontiers in …, 2021 - frontiersin.org
The human face is a highly complex and variable structure resulting from the intricate
coordination of numerous genetic and non-genetic factors. Hundreds of genomic loci …

[HTML][HTML] Integrative analysis of transcriptome dynamics during human craniofacial development identifies candidate disease genes

TN Yankee, S Oh, EW Winchester, A Wilderman… - Nature …, 2023 - nature.com
Craniofacial disorders arise in early pregnancy and are one of the most common congenital
defects. To fully understand how craniofacial disorders arise, it is essential to characterize …