Cytokines and chemokines involved in osteoarthritis pathogenesis

V Molnar, V Matišić, I Kodvanj, R Bjelica… - International journal of …, 2021 - mdpi.com
Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …

Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations

D Primorac, V Molnar, E Rod, Ž Jeleč, F Čukelj… - Genes, 2020 - mdpi.com
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

Microfragmented adipose tissue versus platelet-rich plasma for the treatment of knee osteoarthritis: a prospective randomized controlled trial at 2-year follow-up

S Zaffagnini, L Andriolo, A Boffa… - … American Journal of …, 2022 - journals.sagepub.com
Background: Intra-articular microfragmented adipose tissue (MF-AT) injections have been
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …

Comprehensive review of knee osteoarthritis pharmacological treatment and the latest professional societies' guidelines

D Primorac, V Molnar, V Matišić, D Hudetz, Ž Jeleč… - Pharmaceuticals, 2021 - mdpi.com
Osteoarthritis is the most common musculoskeletal progressive disease, with the knee as
the most commonly affected joint in the human body. While several new medications are still …

Intra-articular injections of mesenchymal stem cells without adjuvant therapies for knee osteoarthritis: a systematic review and meta-analysis

SHS Tan, YT Kwan, WJ Neo… - … American Journal of …, 2021 - journals.sagepub.com
Background: While many reviews have been performed to attempt to provide conclusive
evidence regarding the outcomes of mesenchymal stem cells (MSCs) in osteoarthritis …

Stromal vascular fraction therapy for knee osteoarthritis: a systematic review

A Boada-Pladellorens, M Avellanet… - Therapeutic …, 2022 - journals.sagepub.com
Background: Regenerative cell therapies, such as adipose-derived stromal vascular fraction
(SVF), have been postulated as potential treatments for knee osteoarthritis (KOA) …

Meta-analysis of adipose tissue derived cell-based therapy for the treatment of knee osteoarthritis

N Agarwal, C Mak, C Bojanic, K To, W Khan - Cells, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative disorder associated with cartilage loss and is a leading
cause of disability around the world. In old age, the capacity of cartilage to regenerate is …

Stromal vascular fraction therapy for knee osteoarthritis: A systematic review

EN Goncharov, OA Koval, E Nikolaevich Bezuglov… - Medicina, 2023 - mdpi.com
Background and Objectives: Knee osteoarthritis (OA) is a widespread joint disease, set to
increase due to aging and rising obesity. Beyond cartilage degeneration, OA involves the …

A 24-month follow-up study of the effect of intra-articular injection of autologous microfragmented fat tissue on proteoglycan synthesis in patients with knee …

I Borić, D Hudetz, E Rod, Ž Jeleč, T Vrdoljak, A Skelin… - Genes, 2019 - mdpi.com
Osteoarthritis (OA) is a widely prevalent disease worldwide, and with an increasingly ageing
society, it has become a challenge for the field of regenerative medicine. OA is a disease …

Micro-fragmented adipose tissue (mFAT) associated with arthroscopic debridement provides functional improvement in knee osteoarthritis: a randomized controlled …

M Ulivi, V Meroni, M Viganò, A Colombini… - Knee Surgery, Sports …, 2023 - Springer
Purpose Current conservative treatments for knee OA provide limited benefits, with
symptoms relief for a short amount of time. Regenerative medicine approaches such as the …