Structural biologists have traditionally approached cellular complexity in a reductionist
manner in which the cellular molecular components are fractionated and purified before …

Electron microscopic (EM) tomography is providing important new insights into the internal
organization of mitochondria. The standard baffle model for cristae structure, called into …

The mammalian respiratory chain complexes assemble into supercomplexes (SCs) and
reside in the inner mitochondrial membrane to transfer electrons and establish the proton …

The respiratory chain complexes I, III and IV (CI, CIII and CIV) are present in the bacterial
membrane or the inner mitochondrial membrane and have a role of transferring electrons …

We used electron cryotomography to study the molecular arrangement of large respiratory
chain complexes in mitochondria from bovine heart, potato, and three types of fungi. Long …

The mitochondrial inner membrane can reshape under different physiological conditions.
How, at which frequency this occurs in living cells, and the molecular players involved are …

The light reactions of photosynthesis in green plants are mediated by four large protein
complexes, embedded in the thylakoid membrane of the chloroplast. Photosystem I (PSI) …

The inner membrane of the mitochondrion folds inwards, forming the cristae. This folding
allows a greater amount of membrane to be packed into the mitochondrion. The data in this …

ATP synthase converts the electrochemical potential at the inner mitochondrial membrane
into chemical energy, producing the ATP that powers the cell. Using electron cryo …

Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of
macromolecules at nanometer resolution inside native cells. However, automated …