Enterovirus D68 and acute flaccid myelitis—evaluating the evidence for causality

K Messacar, EJ Asturias, AM Hixon… - The Lancet Infectious …, 2018 - thelancet.com
Increased circulation of enterovirus D68 in 2014 and 2016 temporally and geographically
coincided with increases in cases of acute flaccid myelitis, an uncommon condition of …

Enterovirus 71 infection and vaccines

EJ Yi, YJ Shin, JH Kim, TG Kim… - Clinical and …, 2017 - synapse.koreamed.org
Hand, foot and mouth disease (HFMD) is a highly contagious viral infection affecting young
children during the spring to fall seasons. Recently, serious outbreaks of HFMD were …

Enterovirus and encephalitis

BS Chen, HC Lee, KM Lee, YN Gong… - Frontiers in …, 2020 - frontiersin.org
Enterovirus-induced infection of the central nervous system (CNS) results in acute
inflammation of the brain (encephalitis) and constitutes a significant global burden to human …

Cell surface vimentin is an attachment receptor for enterovirus 71

N Du, H Cong, H Tian, H Zhang, W Zhang… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) is a highly transmissible pathogenic agent that causes
severe central nervous system diseases in infected infants and young children. Here, we …

Transgenic mouse model for the study of enterovirus 71 neuropathogenesis

K Fujii, N Nagata, Y Sato, KC Ong… - Proceedings of the …, 2013 - National Acad Sciences
Enterovirus 71 (EV71) typically causes mild hand-foot-and-mouth disease in children, but it
can also cause severe neurological disease. Recently, epidemic outbreaks of EV71 with …

Type III interferon signaling restricts enterovirus 71 infection of goblet cells

C Good, AI Wells, CB Coyne - Science advances, 2019 - science.org
Recent worldwide outbreaks of enterovirus 71 (EV71) have caused major epidemics of
hand, foot, and mouth disease with severe neurological complications, including acute …

Recent advances in the molecular epidemiology and control of human enterovirus 71 infection

PC McMinn - Current opinion in virology, 2012 - Elsevier
Human enterovirus 71 (HEV71) has emerged as an important cause of viral encephalitis in
the Southeast Asia over the past 15 years. A pattern of increased epidemic activity and …

Cytokine immunopathogenesis of enterovirus 71 brain stem encephalitis

SM Wang, HY Lei, CC Liu - Journal of Immunology Research, 2012 - Wiley Online Library
Enterovirus 71 (EV71) is one of the most important causes of herpangina and hand, foot,
and mouth disease. It can also cause severe complications of the central nervous system …

Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon

BC Ho, IS Yu, LF Lu, A Rudensky, HY Chen… - Nature …, 2014 - nature.com
There are no antivirals or vaccines available to treat Enterovirus 71 (EV71) infections.
Although the type I interferon response, elicited upon virus infection, is critical to establishing …

Immunopathogenesis and virus–host interactions of enterovirus 71 in patients with hand, foot and mouth disease

JA Cox, JA Hiscox, T Solomon, MH Ooi… - Frontiers in …, 2017 - frontiersin.org
Enterovirus 71 (EV71) is a global infectious disease that affects millions of people. The virus
is the main etiological agent for hand, foot, and mouth disease with outbreaks and …