Living in the liver: hepatic infections
The liver has vital metabolic and clearance functions that involve the uptake of nutrients,
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
Screening, prevention and treatment of viral hepatitis B reactivation in patients with haematological malignancies
The prevalence of hepatitis B virus (HBV) infection in patients with haematological
malignancies is increased compared with the general population worldwide. HBV …
malignancies is increased compared with the general population worldwide. HBV …
[HTML][HTML] T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice
K Krebs, N Böttinger, LR Huang, M Chmielewski… - Gastroenterology, 2013 - Elsevier
Background & Aims Antiviral agents suppress hepatitis B virus (HBV) replication but do not
clear the infection. A strong effector T-cell response is required to eradicate HBV, but this …
clear the infection. A strong effector T-cell response is required to eradicate HBV, but this …
[HTML][HTML] Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments
Chronic hepatitis B (CHB) virus infection is a global public health problem, affecting more
than 400 million people worldwide. The clinical spectrum is wide, ranging from a subclinical …
than 400 million people worldwide. The clinical spectrum is wide, ranging from a subclinical …
[HTML][HTML] Enhanced immune response to hepatitis B vaccination through immunization with a Pre-S1/Pre-S2/S vaccine
D Shouval, H Roggendorf, M Roggendorf - Medical microbiology and …, 2015 - Springer
Efficacy and safety of recombinant yeast-derived hepatitis B vaccines for prevention of
hepatitis B have been demonstrated unequivocally worldwide as reflected in reduction in …
hepatitis B have been demonstrated unequivocally worldwide as reflected in reduction in …
Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines
BACKGROUND & AIMS: Virus-specific T cells capable of controlling HBV and eliminating
hepatocellular carcinoma (HCC) expressing HBV antigens are deleted or dysfunctional in …
hepatocellular carcinoma (HCC) expressing HBV antigens are deleted or dysfunctional in …
Hepatitis B: diagnosis, prevention, and treatment
N Gitlin - Clinical chemistry, 1997 - academic.oup.com
Hepatitis B virus (HBV) infection occurs worldwide and is an important cause of acute and
chronic viral hepatitis in the US. In this review, I describe the virus, risk factors for infection …
chronic viral hepatitis in the US. In this review, I describe the virus, risk factors for infection …
HBV life cycle and novel drug targets
D Grimm, R Thimme, HE Blum - Hepatology international, 2011 - Springer
With up to 400 million affected people worldwide, chronic hepatitis B virus (HBV) infection is
still a major health care problem. During the last decade, several novel therapeutic …
still a major health care problem. During the last decade, several novel therapeutic …
[HTML][HTML] Therapeutic vaccines and immune-based therapies for the treatment of chronic hepatitis B: perspectives and challenges
ML Michel, Q Deng, M Mancini-Bourgine - Journal of hepatology, 2011 - Elsevier
The treatment of chronic hepatitis B virus (HBV) infection has greatly improved over the last
10years, but alternative treatments are still needed. Therapeutic vaccination is a promising …
10years, but alternative treatments are still needed. Therapeutic vaccination is a promising …
[PDF][PDF] Clearance of hepatitis B surface antigen after bone marrow transplantation: role of adoptive immunity transfer
Adoptive immunity transfer has been reported to be effective in clearing chronic hepatitis B
virus (HBV) infection. Two hundred twenty‐six patients who received allogeneic bone …
virus (HBV) infection. Two hundred twenty‐six patients who received allogeneic bone …