Sialic acid receptors of viruses

M Matrosovich, G Herrler, HD Klenk - … chemistry and biology II: tools and …, 2015 - Springer
Sialic acid linked to glycoproteins and gangliosides is used by many viruses as a receptor
for cell entry. These viruses include important human and animal pathogens, such as …

Molecular basis of the structure and function of H1 hemagglutinin of influenza virus

N Sriwilaijaroen, Y Suzuki - … of the Japan Academy, Series B, 2012 - jstage.jst.go.jp
Influenza virus hemagglutinin (HA) contains antigenic sites recognized by the host immune
system, cleavage sites cleaved by host proteases, receptor binding sites attaching to sialyl …

Characterization of H7N9 influenza A viruses isolated from humans

T Watanabe, M Kiso, S Fukuyama, N Nakajima, M Imai… - Nature, 2013 - nature.com
Avian influenza A viruses rarely infect humans; however, when human infection and
subsequent human-to-human transmission occurs, worldwide outbreaks (pandemics) can …

[HTML][HTML] Transmission of influenza A viruses

G Neumann, Y Kawaoka - Virology, 2015 - Elsevier
Influenza A viruses cause respiratory infections that range from asymptomatic to deadly in
humans. Widespread outbreaks (pandemics) are attributable to 'novel'viruses that possess a …

Two years after pandemic influenza A/2009/H1N1: what have we learned?

VCC Cheng, KKW To, H Tse, IFN Hung… - Clinical microbiology …, 2012 - Am Soc Microbiol
The world had been anticipating another influenza pandemic since the last one in 1968. The
pandemic influenza A H1N1 2009 virus (A/2009/H1N1) finally arrived, causing the first …

Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic

R Xu, X Zhu, R McBride, CM Nycholat, W Yu… - Journal of …, 2012 - Am Soc Microbiol
The 2009 H1N1 influenza pandemic is the first human pandemic in decades and was of
swine origin. Although swine are believed to be an intermediate host in the emergence of …

Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A (H1N1) 2009 influenza virus

Y Liu, RA Childs, T Matrosovich, S Wharton… - Journal of …, 2010 - Am Soc Microbiol
Mutations in the receptor-binding site of the hemagglutinin of pandemic influenza A (H1N1)
2009 viruses have been detected sporadically. An Asp222Gly (D222G) substitution has …

Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic

R Xu, R McBride, CM Nycholat, JC Paulson… - Journal of …, 2012 - Am Soc Microbiol
Influenza virus hemagglutinin (HA) is the viral envelope protein that mediates viral
attachment to host cells and elicits membrane fusion. The HA receptor-binding specificity is …

A single amino acid in the stalk region of the H1N1pdm influenza virus HA protein affects viral fusion, stability and infectivity

CR Cotter, H Jin, Z Chen - PLoS pathogens, 2014 - journals.plos.org
The 2009 H1N1 pandemic (H1N1pdm) viruses have evolved to contain an E47K substitution
in the HA2 subunit of the stalk region of the hemagglutinin (HA) protein. The biological …

Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site

M Hong, PS Lee, RMB Hoffman, X Zhu… - Journal of …, 2013 - Am Soc Microbiol
Influenza virus is a global health concern due to its unpredictable pandemic potential. This
potential threat was realized in 2009 when an H1N1 virus emerged that resembled the 1918 …