Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

The role of leptin and adiponectin in obesity-associated cognitive decline and Alzheimer's disease

L Forny-Germano, FG De Felice… - Frontiers in …, 2019 - frontiersin.org
Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

ESPEN guideline clinical nutrition in neurology

R Burgos, I Bretón, E Cereda, JC Desport, R Dziewas… - Clinical Nutrition, 2018 - Elsevier
Neurological diseases are frequently associated with swallowing disorders and malnutrition.
Moreover, patients with neurological diseases are at increased risk of micronutrient …

Effect of nutrition on neurodegenerative diseases. A systematic review

VE Bianchi, PF Herrera, R Laura - Nutritional neuroscience, 2021 - Taylor & Francis
Neurodegenerative diseases are characterized by the progressive functional loss of
neurons in the brain, causing cognitive impairment and motoneuron disability. Although …

Effect of high‐caloric nutrition on survival in amyotrophic lateral sclerosis

AC Ludolph, J Dorst, J Dreyhaupt… - Annals of …, 2020 - Wiley Online Library
Objective Weight loss has been identified as a negative prognostic factor in amyotrophic
lateral sclerosis, but there is no evidence regarding whether a high‐caloric diet increases …

Nutritional and metabolic factors in amyotrophic lateral sclerosis

A Ludolph, L Dupuis, E Kasarskis, F Steyn… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …

Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis

MD Wang, J Little, J Gomes, NR Cashman, D Krewski - Neurotoxicology, 2017 - Elsevier
Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150
years ago, risk factors related to the onset and progression of ALS remain largely unknown …

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis

E D'Amico, P Factor-Litvak, RM Santella… - Free radical biology and …, 2013 - Elsevier
Sporadic amyotrophic lateral sclerosis (ALS) is one of the most devastating neurological
diseases; most patients die within 3 to 4 years after symptom onset. Oxidative stress is a …

CNS glucose metabolism in Amyotrophic Lateral Sclerosis: a therapeutic target?

TW Tefera, FJ Steyn, ST Ngo, K Borges - Cell & bioscience, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder
primarily characterized by selective degeneration of both the upper motor neurons in the …

Ketogenic diet in neuromuscular and neurodegenerative diseases

A Paoli, A Bianco, E Damiani… - BioMed research …, 2014 - Wiley Online Library
An increasing number of data demonstrate the utility of ketogenic diets in a variety of
metabolic diseases as obesity, metabolic syndrome, and diabetes. In regard to neurological …