Vitiligo: a focus on pathogenesis and its therapeutic implications

C Bergqvist, K Ezzedine - The Journal of dermatology, 2021 - Wiley Online Library
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …

Update on the pathogenesis of vitiligo

HZ Marchioro, CCS Castro, VM Fava… - Anais Brasileiros de …, 2022 - SciELO Brasil
Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …

Vitiligo: a comprehensive overview: part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work …

A Alikhan, LM Felsten, M Daly… - Journal of the American …, 2011 - Elsevier
Vitiligo is an acquired pigmentary disorder of unknown etiology that is clinically
characterized by the development of white macules related to the selective loss of …

Genetics of population isolates

M Arcos‐Burgos, M Muenke - Clinical genetics, 2002 - Wiley Online Library
Genetic isolates, as shown empirically by the Finnish, Old Order Amish, Hutterites, Sardinian
and Jewish communities among others, represent a most important and powerful tool in …

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC

C Quan, YQ Ren, LH Xiang, LD Sun, AE Xu, XH Gao… - Nature …, 2010 - nature.com
We conducted a genome-wide association study of generalized vitiligo in the Chinese Han
population by genotyping 1,117 cases and 1,429 controls. The 34 most promising SNPs …

[HTML][HTML] The genetic basis of vitiligo

RA Spritz, SA Santorico - Journal of Investigative Dermatology, 2021 - Elsevier
Vitiligo is a complex disease in which autoimmune destruction of epidermal melanocytes
results in patches of depigmented white skin. Vitiligo has an estimated prevalence of about …

Relevance of thyroiditis and of other autoimmune diseases in children with vitiligo

P Iacovelli, JLM Sinagra, AP Vidolin, S Marenda… - Dermatology, 2004 - karger.com
Background: Studies that clearly define the possible association of childhood vitiligo with
autoimmune and/or endocrine diseases are lacking. Objective: To examine the presence of …

Physiopathology and genetics of vitiligo

T Passeron, JP Ortonne - Journal of autoimmunity, 2005 - Elsevier
Generalized vitiligo is an acquired disorder in which white patches of skin and overlying hair
result from autoimmune loss of melanocytes from involved areas. The autoimmune …

The genetics of generalized vitiligo and associated autoimmune diseases

RA Spritz - Pigment Cell Research, 2007 - Wiley Online Library
Vitiligo is an acquired disorder in which patches of depigmented skin and often overlying
hair, and mucous membranes, are the result of progressive autoimmune loss of melanocytes …

The genetics of generalized vitiligo

RA Spritz - Dermatologic immunity, 2008 - karger.com
Generalized vitiligo is an acquired disorder in which patches of depigmented skin, overlying
hair and oral mucosa result from progressive autoimmune loss of melanocytes from the …