Complement system part I–molecular mechanisms of activation and regulation

NS Merle, SE Church, V Fremeaux-Bacchi… - Frontiers in …, 2015 - frontiersin.org
Complement is a complex innate immune surveillance system, playing a key role in defense
against pathogens and in host homeostasis. The complement system is initiated by …

Complement evasion: an effective strategy that parasites utilize to survive in the host

S Shao, X Sun, Y Chen, B Zhan, X Zhu - Frontiers in microbiology, 2019 - frontiersin.org
Parasitic infections induce host immune responses that eliminate the invading parasites.
However, parasites have evolved to develop many strategies to evade host immune attacks …

Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus

AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …

Possible mechanisms of C-reactive protein mediated acute myocardial infarction

PA Fordjour, Y Wang, Y Shi, K Agyemang… - European journal of …, 2015 - Elsevier
Myocardial infarction is a relevant cardiovascular event worldwide for morbidity and
mortality. It has been theorized that acute myocardial infarctions (AMIs) and other acute …

[HTML][HTML] Structure insights of SARS-CoV-2 open state envelope protein and inhibiting through active phytochemical of ayurvedic medicinal plants from Withania …

RA Alharbi - Saudi Journal of Biological Sciences, 2021 - Elsevier
Coronaviruses have been causing pandemic situations across the globe for the past two
decades and the focus is on identifying suitable novel targets for antivirals and vaccine …

Shared weapons of blood-and plant-feeding insects: surprising commonalities for manipulating hosts

A Guiguet, G Dubreuil, MO Harris, HM Appel… - Journal of Insect …, 2016 - Elsevier
Insects that reprogram host plants during colonization remind us that the insect side of plant–
insect story is just as interesting as the plant side. Insect effectors secreted by the salivary …

The secretome of filarial nematodes and its role in host-parasite interactions and pathogenicity in onchocerciasis-associated epilepsy

A Hotterbeekx, J Perneel, MK Vieri… - Frontiers in Cellular …, 2021 - frontiersin.org
Filarial nematodes secrete bioactive molecules which are of interest as potential mediators
for manipulating host biology, as they are readily available at the host-parasite interface. The …

Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy

L Zhao, S Shao, Y Chen, X Sun, R Sun… - Frontiers in …, 2017 - frontiersin.org
As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses
by producing a variety of immunomodulatory molecules to escape from host immune attack …

Trichinella spiralis Calreticulin S-Domain Binds to Human Complement C1q to Interfere With C1q-Mediated Immune Functions

S Shao, C Hao, B Zhan, Q Zhuang, L Zhao… - Frontiers in …, 2020 - frontiersin.org
Helminths develop strategies to escape host immune responses that facilitate their survival
in the hostile host immune environment. Trichinella spiralis, a tissue-dwelling nematode, has …

The many faces of parasite calreticulin

D Esperante, A Flisser, F Mendlovic - Frontiers in Immunology, 2023 - frontiersin.org
Calreticulin from parasites and its vertebrate hosts share~ 50% identity and many of its
functions are equally conserved. However, the existing amino acid differences can affect its …