Thermophilic cell factories have remarkably broad potential for industrial applications, but
are limited by a lack of genetic manipulation tools and recalcitrance to transformation. Here …

The production and application of biodegradable polylactic acid are still severely hindered
by the cost of its polymer-grade lactic acid monomers. High-temperature biomanufacturing …

High performance is the core objective that biotechnologists pursue, of which low efficiency,
low titer, and side products are the chief obstacles. Here, a thermal strategy is proposed for …

Nutraceuticals are defined as food or food components with therapeutic capabilities that
have few side effects and are regarded as a natural therapy for preventing the onset of …

Because of the discovery of various thermophiles, high-temperature fermentation is an
emerging technology for efficient biomanufacturing with decreased cooling cost and risk for …

Summary l-Alanine is an important amino acid widely used in food, medicine, materials, and
other fields. Here, we develop Bacillus licheniformis as an efficient l-alanine microbial cell …

Optically pure lactic acid is an important precursor for the synthesis of biodegradable plastic
polylactic acid. Geobacillus thermoglucosidasius is a thermophilic bacterial chassis with …