Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines

SJ Lim, ND Muhd Noor, S Sabri… - Medical …, 2024 - academic.oup.com
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …

Biased eviction of variant histone H3 nucleosomes triggers biofilm growth in Candida albicans

P Brahma, R Aggarwal, K Sanyal - Mbio, 2023 - Am Soc Microbiol
Candida albicans is an opportunistic human pathogen that colonizes the gastrointestinal
and genitourinary tracts of healthy individuals. C. albicans yeast cells can switch to …

Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor

Z Wang, L Yin, Y Qi, J Zhang, H Zhu… - Frontiers in Microbiology, 2022 - frontiersin.org
Colonization of the intestinal tract by Candida albicans (C. albicans) can lead to invasive
candidiasis. Therefore, a functional intestinal epithelial barrier is critical for protecting …

Negative regulation of biofilm development by the CUG‐Ser1 clade‐specific histone H3 variant is dependent on the canonical histone chaperone CAF‐1 complex in …

R Singha, R Aggarwal, K Sanyal - Molecular Microbiology, 2023 - Wiley Online Library
The CUG‐Ser1 clade‐specific histone H3 variant (H3VCTG) has been reported to be a
negative regulator of planktonic to biofilm growth transition in Candida albicans. The …

Histone deacetylase Sir2 promotes the systemic Candida albicans infection by facilitating its immune escape via remodeling the cell wall and maintaining the …

C Yang, G Li, Q Zhang, W Bai, Q Li, P Zhang, J Zhang - Mbio, 2024 - Am Soc Microbiol
Histone deacetylation affects Candida albicans (C. albicans) pathogenicity by modulating
virulence factor expression and DNA damage. The histone deacetylase Sir2 is associated …

Loss of the accessory chromosome converts a pathogenic tree-root fungus into a mutualistic endophyte

H Wei, Z Zhong, Z Li, Y Zhang, EH Stukenbrock… - Plant …, 2024 - cell.com
Some fungal accessory chromosomes (ACs) may contribute to virulence in plants. However,
the mechanisms by which ACs determine specific traits associated with lifestyle transitions …

Responses of dinoflagellate cells to ultraviolet‐C irradiation

ACM Kwok, C Li, WT Lam… - Environmental …, 2022 - Wiley Online Library
Dinoflagellates are important aquatic microbes and major harmful algal bloom (HAB) agents
that form invasive species through ship ballast transfer. UV‐C installations are …

AJ domain protein functions as a histone chaperone to maintain genome integrity and the response to DNA damage in a human fungal pathogen

LC Horianopoulos, CWJ Lee, K Schmitt, O Valerius… - mbio, 2021 - Am Soc Microbiol
Histone chaperoning ensures genomic integrity during routine processes such as DNA
replication and transcription as well as DNA repair upon damage. Here, we identify a …

Candida albicans a comprehensive view of the proteome

L Gomez Artiguez, S de la Camara Fuentes, Z Sun… - bioRxiv, 2024 - biorxiv.org
We describe a new release of the Candida albicans PeptideAtlas proteomics spectral
resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein …

[PDF][PDF] Chromatin Accessibility Contributes to Candida albicans Adaptation to Echinocandins

SK Sah, A Yadav, T Stahl, JJ Hayes, M Bulger… - 2024 - preprints.org
Infections by the major opportunistic pathogen of human Candida albicans are commonly
treated with echinocandin (ECN) drugs. However, C. albicans can adapt to grow in the …