Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

J Wei, M Li, C Xue, S Chen, L Zheng, H Deng… - Journal of Experimental …, 2023 - Springer
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …

Decision-level fusion classification of ovarian CT benign and malignant tumors based on radiomics and deep learning of dual views

Q Rong, W Wu, Z Lu, S Liao - IEEE Access, 2024 - ieeexplore.ieee.org
Ovarian cancer is one of the most prevalent malignant tumors in the female reproductive
system, and its early diagnosis has always posed a challenge. Computed tomography (CT) …

The WATCH-DM risk score estimates clinical outcomes in type 2 diabetic patients with heart failure with preserved ejection fraction

K Iwakura, T Onishi, A Okamura, Y Koyama… - Scientific Reports, 2024 - nature.com
The coexistence of heart failure is frequent and associated with higher mortality in patients
with type 2 diabetes (T2DM), and its management is a critical issue. The WATCH-DM risk …

[HTML][HTML] Cancer-associated fibroblast-derived gene signature discriminates distinct prognoses by integrated single-cell and bulk RNA-seq analyses in breast cancer

Z Fang, YL Han, ZJ Gao, F Yao - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Cancer-associated fibroblasts (CAFs) are one of the most predominant cellular
subpopulations in the tumor stroma and play an integral role in cancer occurrence and …

[PDF][PDF] Unified ROC Curve Estimator for Diagnosis and Prognosis Studies: The sMSROC Package.

S Díaz-Coto, P Martínez-Camblor, N Corral-Blanco - R J., 2024 - journal.r-project.org
The binary classification problem is a hot topic in Statistics. Its close relationship with the
diagnosis and the prognosis of diseases makes it crucial in biomedical research. In this …

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent …

DJ Glazar, S Sahebjam, HHM Yu… - CPT …, 2024 - Wiley Online Library
Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median
progression‐free survival (PFS) of< 7 months. Responses to treatment are heterogenous …

Integration of osimertinib-targeted EGFR gene-associated differential gene expression in constructing a prognostic model for lung adenocarcinoma

H Li, L Yang, Q Yang, Z Liang, W Su, L Yu - Functional & Integrative …, 2024 - Springer
Lung adenocarcinoma (LUAD) is one of the deadliest cancers. Epidermal growth factor
receptor-tyrosine kinase inhibitor (EGFR-TKI)-targeted therapy is an important approach for …

Time-dependent receiver operating characteristic curve estimator for correlated right-censored time-to-event data

KM Beyene, DG Chen - Statistical Methods in Medical …, 2024 - journals.sagepub.com
In clinical trials, evaluating the accuracy of risk scores (markers) derived from prognostic
models for prediction of survival outcomes is of major concern. The time-dependent receiver …

A novel nonparametric time‐dependent precision–recall curve estimator for right‐censored survival data

KM Beyene, DG Chen, YG Kifle - Biometrical Journal, 2024 - Wiley Online Library
In order to assess prognostic risk for individuals in precision health research, risk prediction
models are increasingly used, in which statistical models are used to estimate the risk of …

[HTML][HTML] Construction and analysis of a reliable five-gene prognostic signature for colon adenocarcinoma associated with the wild-type allelic state of the COL6A6 …

Q Liu, X Zhang, Y Song, J Si, Z Li… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Background Tumors emerge by acquiring a number of mutations over time. The first
mutation provides a selective growth advantage compared to adjacent epithelial cells …