Intracellular antibodies (intrabodies) are recombinant antibody fragments that bind to target
proteins expressed inside of the same living cell producing the antibodies. The molecules …

Nature has provided prodigious reservoirs of pharmacologically active compounds for drug
development since times. Physcion and physcion 8-O-β-D-glucopyranoside (PG) are …

To interfere with cell function, many scientists rely on methods that target DNA or RNA due to
the ease with which they can be applied. Proteins are usually the final executors of function …

Objective To evaluate the therapeutic effect of Chlorin e6 photodynamic therapy (Ce6-PDT)
in human colorectal cancer cells and investigate the role of autophagy in Ce6-PDT. Methods …

Icaritin, a hydrolytic product of icariin from the Epimedium genus, exerts anti‐tumour effects
on a variety of tumour cell types, mainly by inhibiting cell proliferation and inducing …

Background: Gastric cancer (GC) is one of the major malignancies threatening human lives
and health. Non-SMC condensin II complex subunit D3 (NCAPD3) plays a crucial role in the …

Cancer stem cells reside in a distinct region within the tumor microenvironment that it is
believed to play a fundamental role in regulating stemness, proliferation, survival, and …

Pituitary tumor transforming gene (PTTG) is a novel oncogene that is expressed at higher
level in most of the tumors. PTTG overexpression correlates with lymph node infiltration and …

Abstract Domain 1 of CD147 participates in matrix metalloproteinase (MMP) production and
is a candidate for targeted therapy to prevent cancer invasion and metastasis. A functional …

Aims In the presence of oxygen, most of the synthesized pyruvate during glycolysis in the
cancer cell of solid tumors is released away from the mitochondria to form lactate (Warburg …