In the search for new therapeutic agents for currently incurable diseases, attention has
turned to traditionally “undruggable” targets, and collections of drug-like small molecules …

Articular cartilage (AC) has no or very low ability of self-repair, and untreated lesions may
lead to the development of osteoarthritis. One method that has been proven to result in long …

Tissue constructs for cartilage with native mechanical properties have not been described to
date. To address this need the bacterial cellulose (BC) secreted by Gluconacetobacter …

PURPOSE: The aim of the study was to determine if isolated mesenchymal stem cells
(MSCs) derived from the infrapatellar fat pad could effectively improve clinical results when …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

Human embryonic stem cells (hESCs) have the potential to offer a virtually unlimited source
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …

OBJECTIVE: Adult articular cartilage shows a limited intrinsic repair response to traumatic
injury. To regenerate damaged cartilage, cell-assisted repair is thus viewed as a promising …

The aim of the present study was to evaluate the capability of novel biodegradable
polyurethane scaffolds to support attachment, growth and maintenance of differentiated …

Owing to the limited repair capacity of articular cartilage, it is essential to develop tissue-
engineered cartilage for patients suffering from joint disease and trauma. Herein, we …

A major area in regenerative medicine is the application of stem cells in cartilage tissue
engineering and reconstructive surgery. This requires well‐defined and efficient protocols …